ATI RN
ATI Pharmacology Practice Exam B Questions
Question 1 of 5
The pharmacological property of aspirin comes from its ability to inhibit the synthesis of :
Correct Answer: A
Rationale: Aspirin exerts its pharmacological effects by inhibiting the synthesis of eicosanoids. Eicosanoids are signaling molecules that play a key role in inflammation, pain, and fever. Specifically, aspirin inhibits the enzyme cyclooxygenase (COX), which is crucial for the production of prostaglandins from arachidonic acid. By blocking COX, aspirin reduces the formation of pro-inflammatory prostaglandins, ultimately leading to its anti-inflammatory, analgesic, and antipyretic effects. This mechanism also accounts for aspirin's ability to inhibit platelet aggregation, which is why it is commonly used as an antithrombotic agent.
Question 2 of 5
Which action is most important for the nurse to teach a patient who is taking tositumomab?
Correct Answer: C
Rationale: Tositumomab is a radioactive monoclonal antibody used in cancer treatment. Patients should be advised to use a separate bathroom and sit while urinating to minimize radiation exposure to others and themselves. This precaution is necessary because the drug is excreted in urine, which remains radioactive for a period after treatment. Avoiding alcohol or smoking is not specifically related to tositumomab therapy. Taking the drug on an empty stomach is not applicable, as it is administered intravenously.
Question 3 of 5
A patient being seen for skin concerns asks, 'What do keratolytic drugs remove?' What is the nurse’s best response?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
The nurse is reviewing new medication orders that have been written for a newly admitted patient. The nurse will need to clarify which orders? Select all that apply.
Correct Answer: D
Rationale: Medication orders must be clear, complete, and appropriate for the patient's condition. Orders that include 'as needed' (PRN) medications, such as 'Docusate (Colace) as needed for constipation,' require clarification because they lack specific dosing instructions. The nurse must confirm the frequency, dosage, and indications for PRN medications to ensure safe administration. The other orders (Metformin, Sitagliptin, Simvastatin, and Irbesartan) are complete and do not require clarification. Therefore, the nurse should focus on clarifying the PRN order to avoid errors in medication administration.
Question 5 of 5
Chris asks the nurse whether all donor blood products are cross-matched with the recipient to prevent a transfusion reaction. Which of the following always require cross-matching?
Correct Answer: D
Rationale: Packed red blood cells (PRBCs) always require cross-matching to ensure compatibility between the donor and recipient blood types. Cross-matching involves testing the recipient's serum against the donor's red cells to detect antibodies that could cause a transfusion reaction. Granulocytes, platelets, and plasma do not require cross-matching in the same way, although they may undergo other compatibility tests. PRBCs are the most critical to match correctly due to the risk of hemolytic reactions, which can be life-threatening.