ATI RN
Pediatric Immunization Test Questions Questions
Question 1 of 5
The person in the above question is experiencing a primary infection with the virus. B cells activated in a primary infection secrete which class of antibody first?
Correct Answer: D
Rationale: IgM is the first antibody produced in a primary immune response.
Question 2 of 5
Which of the following molecules triggers the caspase cascade And through which cells
Correct Answer: A
Rationale: Perforin and granzymes from CD8 T cells trigger caspase-mediated apoptosis in target cells.
Question 3 of 5
A 2-year-old boy presented with failure to thrive, neonatal hypocalcemic seizure, and three attacks of sepsis. Examination reveals cleft palate and holo-systolic murmur. Of the following, the genetic predisposition of this condition is
Correct Answer: A
Rationale: These features (hypocalcemia, heart defect, cleft palate) are classic for DiGeorge syndrome, caused by 22q11.2 microdeletion.
Question 4 of 5
The following conditions can cause eosinophilia EXCEPT
Correct Answer: A
Rationale: Malaria typically does not cause eosinophilia; it's more associated with anemia or leukocytosis. The others are parasitic infections known to increase eosinophils.
Question 5 of 5
A 13-month-old girl presented with failure to thrive, repeated chest infection, and fatty offensive diarrhea. Hemoglobin level 8.8 gm/dl, platelate count 150/mm3, white blood cell count 3.500/mm3, with absolute neutrophil count (ANC) 500/μL. Of the following, the MOST likely diagnosis is
Correct Answer: D
Rationale: Shwachman-Diamond syndrome features neutropenia, pancreatic insufficiency (fatty diarrhea), and failure to thrive, matching this presentation.