The percentage of individuals with congenital heart defects is highest in

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Pediatric Endocrine Nursing Questions Questions

Question 1 of 5

The percentage of individuals with congenital heart defects is highest in

Correct Answer: B

Rationale: In Turner syndrome about 50%, Williams syndrome 80% (supravalvar aortic and pulmonic stenosis being common), Down syndrome 50%, and lower rates in Cri du Chat (15-20%), making Williams syndrome the highest.

Question 2 of 5

Matching: Match the disease with its enzyme - β-Glucosidase

Correct Answer: B

Rationale: Gaucher disease results from β-glucosidase (glucocerebrosidase) deficiency, causing glucocerebroside accumulation.

Question 3 of 5

Of the following physical findings found in some patients with hyperlipidemia, which one is most likely to be found in a 17-year-old boy with heterozygous familial hypercholesterolemia?

Correct Answer: D

Rationale: Heterozygous familial hypercholesterolemia often causes tendon xanthomas, especially Achilles, in adolescents/young adults.

Question 4 of 5

The lipid storage diseases are a group of disorders that result from specific enzymatic deficiencies. Each statement about these disorders is true EXCEPT

Correct Answer: B

Rationale: Diagnosis typically uses leukocyte enzyme assays or genetic testing, not liver biopsy, which is invasive and less common.

Question 5 of 5

The most useful therapeutic approach to the patient in the previous two questions is

Correct Answer: C

Rationale: NTBC (nitisinone) is the standard treatment for tyrosinemia type I, reducing toxic metabolites.

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