The patient accidentally takes too much of the prescribed warfarin (Coumadin) and is readmitted to the hospital with bleeding. Which drug can the nurse anticipates administrating?

Correct Answer: D

Rationale: In the scenario described where the patient has accidentally taken too much warfarin (Coumadin) and is experiencing bleeding, the nurse can anticipate administering Vitamin K. Warfarin is an anticoagulant medication that works by inhibiting vitamin K-dependent clotting factors in the liver. By administering Vitamin K, it helps reverse the anticoagulant effect of warfarin by supplying the needed vitamin K for the production of clotting factors. This aids in the clotting process and helps to stop the bleeding that may occur due to excess warfarin in the system. Other medications listed (such as Protamine sulfate, Alteplase, Reteplase) are not specific antidotes for warfarin overdose-related bleeding but are used for different therapeutic purposes.

Correct Answer: B

Rationale: Protamine is the antidote for Heparin. Heparin is an anticoagulant medication that works by increasing the activity of antithrombin III, leading to the inhibition of clotting factors. In cases of excessive bleeding or overdose with Heparin, protamine can be administered to neutralize its anticoagulant effects. Protamine works by binding to heparin to form a stable complex, thereby reversing the anticoagulant activity of Heparin. It is important for healthcare providers to be familiar with the antidotes for various medications to manage potential complications effectively.

Correct Answer: C

Rationale: Lactic acidosis is an adverse effect specific to the biguanide diabetic drug metformin. It is a rare but serious complication associated with the use of metformin. Lactic acidosis occurs when there is a buildup of lactate in the body, leading to a decrease in pH levels. This condition can be life-threatening and requires immediate medical attention. Symptoms of lactic acidosis include rapid breathing, muscle pain or weakness, abdominal pain, dizziness, and irregular heartbeat. It is important for individuals taking metformin to be aware of the signs and symptoms of lactic acidosis and seek medical help if they experience them.

Correct Answer: C

Rationale: Valproate belongs to the category class of anticonvulsants, which means it is primarily used to treat seizures and epilepsy. Additionally, valproate also has properties that make it effective in the treatment of vascular headaches, such as migraines. It is not an anticoagulant, antianxiety medication like benzodiazepines, or a mood stabilizer.

Correct Answer: B

Rationale: St. John's Wort is known to interact with phenytoin, a drug commonly used to treat seizures. St. John's Wort can decrease the effectiveness of phenytoin by increasing its metabolism in the liver. This interaction can lead to lower levels of phenytoin in the bloodstream, potentially reducing its therapeutic effects and increasing the risk of seizure recurrence. It is important for individuals taking phenytoin to avoid using St. John's Wort to prevent this drug interaction.