ATI RN
Immune System Medication Questions
Question 1 of 5
The nursing class is studying monoclonal antibodies. What monoclonal antibody reacts to human T cells, disabling them and acting as an immune suppressor?
Correct Answer: D
Rationale: The correct answer is D, Muromonab-CD3. This monoclonal antibody specifically targets and reacts with human T cells, disabling them and acting as an immune suppressor. Muromonab-CD3 is used in conditions where T cells need to be suppressed, such as in transplant rejection. A: Adalimumab targets tumor necrosis factor-alpha, not T cells. B: Cetuximab targets epidermal growth factor receptor, not T cells. C: Rituximab targets CD20 antigen on B cells, not T cells.
Question 2 of 5
The nurse is caring for a female patient, aged 62, who has been admitted for treatment of metastatic melanoma. What agent would the nurse anticipate the physician is likely to order?
Correct Answer: D
Rationale: The correct answer is D: Ipilimumab. This drug is a checkpoint inhibitor used in the treatment of metastatic melanoma by enhancing the immune system to fight cancer cells. It is a common choice for this condition due to its effectiveness. Aldesleukin (A) and Interferon alfa 2b (B) are also immunotherapy agents but are not typically used as first-line treatments for metastatic melanoma. Cyclosporine (C) is an immunosuppressant used to prevent organ transplant rejection and manage autoimmune diseases, not for treating melanoma.
Question 3 of 5
What interleukin receptor antagonist would the nurse anticipate is most likely to be ordered for a patient, 25 years old, who has not responded to traditional antirheumatic drugs?
Correct Answer: B
Rationale: The correct answer is B: Anakinra (Kineret). Anakinra is an interleukin-1 receptor antagonist, which is used to treat patients with rheumatoid arthritis who have not responded to traditional antirheumatic drugs. Interleukin-1 is a key cytokine involved in the inflammatory response seen in rheumatoid arthritis. By blocking the action of interleukin-1, Anakinra helps reduce inflammation and joint damage in these patients. A: Natalizumab (Tysabri) is a monoclonal antibody used to treat multiple sclerosis by preventing immune cells from crossing the blood-brain barrier. C: Eculizumab (Soliris) is a monoclonal antibody used to treat rare blood disorders by blocking a specific part of the immune system. D: Adalimumab (Humira) is a tumor necrosis factor (TNF) inhibitor used to treat various autoimmune diseases like rheumatoid arthritis, ps
Question 4 of 5
The patient has arrived in the short stay unit for an infusion of tositumomab with 131 tositumomab (Bexxar). Before beginning the infusion, the nurse assesses the patient's vital signs and finds the patient has a temperature of 101.5°F, What is the nurse's priority action?
Correct Answer: D
Rationale: The correct answer is D: Treating the fever before beginning the therapy. Fever can be a sign of infection or other serious underlying issues. Before starting the infusion, it is crucial to address the fever to prevent potential complications. The step-by-step rationale is: 1. Assess the patient's vital signs - In this case, the patient has a temperature of 101.5°F. 2. Recognize the significance of fever - Fever can indicate infection or other health concerns. 3. Prioritize patient safety - Treating the fever before starting the infusion ensures the patient's well-being. 4. Prevent potential adverse reactions - Infusing tositumomab with a fever could exacerbate the patient's condition. 5. Collaborate with the healthcare team - Once the fever is treated, the therapy can be safely initiated. Incorrect Choices: A: Holding the infusion until the patient is afebrile - This delays necessary treatment and does not address the underlying issue causing
Question 5 of 5
The nurse is writing a plan of care for a patient receiving immune suppressants for leukemia. What would be an appropriate nursing diagnosis for this patient?
Correct Answer: B
Rationale: The correct answer is B: Acute pain related to central nervous system (CNS), gastrointestinal (GI), and flu-like effects. This nursing diagnosis is appropriate for a patient receiving immune suppressants for leukemia as these medications can cause adverse effects such as CNS, GI, and flu-like symptoms leading to acute pain. The nurse should assess the patient for these symptoms and provide interventions to manage pain effectively. Incorrect Choices: A: Anxiety related to diagnosis and drug therapy - While anxiety can be common in patients with leukemia and receiving immune suppressants, acute pain is a more specific and immediate concern that should be addressed first. C: Risk for infection related to immune stimulation - This is not the most immediate concern for a patient receiving immune suppressants, as the main focus should be on managing side effects such as pain. D: Imbalanced nutrition: More than body requirements - This nursing diagnosis is not directly related to the side effects of immune suppressants and would not be the priority for this patient.