ATI RN
ATI Practice Exam Pharmacology The Endocrine System Questions
Question 1 of 5
The nurse reviews the list of medications and is aware that red blood cell production can be stimulated with which drug for anemia?
Correct Answer: A
Rationale: Epoetin alfa is a recombinant form of erythropoietin, a hormone that stimulates red blood cell production. It is used to treat anemia, particularly in patients with chronic kidney disease or those undergoing chemotherapy. Filgrastim and sargramostim stimulate white blood cell production, while interleukin 2 is used to boost the immune system. The nurse should recognize epoetin alfa as the appropriate drug for managing anemia and monitor the patient's hemoglobin levels during treatment.
Question 2 of 5
A patient has just received a prescription for an enteric-coated stool softener. When teaching the patient, the nurse should include which statement?
Correct Answer: D
Rationale: Enteric-coated medications are designed to resist dissolution in the stomach and release the active ingredient in the intestines. Chewing or crushing the tablet can compromise the coating, leading to premature drug release and potential irritation of the stomach lining. Therefore, the nurse should instruct the patient to swallow the tablet whole without chewing. Taking the tablet with orange juice or avoiding other medications is not necessary, and crushing the tablet is contraindicated. Proper administration ensures the medication's effectiveness and minimizes the risk of adverse effects.
Question 3 of 5
A neighbor tells nurse Maureen he has to have surgery and is reluctant to have any blood product transfusions because of a fear of contracting an infection. He asks the nurse what are his options. The nurse teaches the person that the safest blood product is:
Correct Answer: C
Rationale: An autologous blood product is the safest option because it involves the patient donating their own blood before surgery, eliminating the risk of transfusion reactions or infections from donor blood. Allogeneic products come from other donors and carry a small risk of infection or incompatibility. Directed donations are from known donors but still carry some risks. Cross-matching ensures compatibility but does not eliminate infection risks. Therefore, autologous donation is the safest choice.
Question 4 of 5
Which of the following is least likely to have an adverse drug interaction with phenelzine (a monoamine oxidase (MAO) inhibitor)?
Correct Answer: D
Rationale: Phenelzine, an MAOI, risks hypertensive crisis or serotonin syndrome with drugs increasing monoamines. Levodopa raises catecholamines, risking hypertension with MAOIs. Ropinirole, a dopamine agonist, may enhance monoamine effects, potentially hazardous. Tolcapone, a COMT inhibitor, increases levodopa levels, amplifying MAOI risks. Pseudoephedrine, a sympathomimetic, causes severe hypertension. Propofol, an anesthetic, acts via GABA without monoamine interaction, making it least likely to cause adverse effects with phenelzine. Its safety profile here is key for procedural use in MAOI patients.
Question 5 of 5
Warfarin:
Correct Answer: C
Rationale: Warfarin is highly bioavailable (near 100%), so 90% is close and true. It doesn't inactivate vitamin K but inhibits vitamin K epoxide reductase, reducing clotting factor synthesis, making that false. It can paradoxically cause venous thrombosis (e.g., skin necrosis) early in therapy due to protein C depletion, a true statement. Initial loading is typically 5-10 mg, not 0.5 mg, so that's false. Metronidazole increases its effect via metabolism inhibition, not bactericidal action. The thrombosis risk is a rare but serious side effect, highlighting the need for bridging with heparin during initiation.