ATI RN
ATI Pharmacology Practice A Questions
Question 1 of 5
The nurse plans to teach a class on anabolic steroids to a group of high school athletes. What will the best plan by the nurse include?
Correct Answer: A
Rationale: Anabolic steroids, synthetic testosterone derivatives, suppress natural hormone production, including spermatogenesis, leading to infertility-a critical risk for young athletes to understand. They also impact the entire body, notably causing liver damage (e.g., hepatotoxicity or tumors), a systemic effect worth noting. However, while effective for muscle growth, weight training surpasses steroids in safety and sustainability, debunking the ‘most effective' claim. Aggression, or ‘roid rage,' is a well-documented behavioral change due to hormonal imbalance, making it another key point. Infertility stands out in education, as it's a direct, long-term consequence tied to reproductive health, resonating with teens' future planning, and is supported by evidence of testicular atrophy and reduced sperm count, distinguishing it from broader effects or myths about efficacy.
Question 2 of 5
The nurse teaching a pre-conception class would tell participants that they should be most careful about exposure to drugs during which stage of pregnancy?
Correct Answer: D
Rationale: The embryonic stage (weeks 3-8) is peak risk-organogenesis makes fetuses vulnerable to teratogens (e.g., alcohol causing FAS), per developmental biology. Equal risk ignores stages. Pre-implantation (pre-week 3) has less organ impact. Third trimester affects growth, less malformation. Embryonic caution is critical, shaping warnings.
Question 3 of 5
A 40-year-old patient experiencing periods of mania and periods of depression would most likely benefit from which of the following?
Correct Answer: D
Rationale: Carbamazepine, a mood stabilizer, treats bipolar mania/depression-per psychiatry-unlike atomoxetine (ADHD), amitriptyline (depression), or methylphenidate (ADHD). It fits cycles, per evidence.
Question 4 of 5
A 23-year-old man is a driver who is involved in a motor vehicle accident. He is found to have a blood alcohol level of 850 mg/dL. Because of the way the body handles ethanol, the conventional 'half-life' to describe its metabolism does not apply. Which of the following drugs at therapeutic concentrations exhibits the same property?
Correct Answer: B
Rationale: Ethanol's zero-order metabolism (constant rate) differs from first-order half-life kinetics. Phenytoin shares this-saturating hepatic enzymes at therapeutic levels, making it correct. Ibuprofen , Simvastatin , Tolbutamide , and Valproic acid (E) follow first-order kinetics. Phenytoin's saturation mimics ethanol's fixed clearance, relevant to toxicology.
Question 5 of 5
An 18-year-old college student is hanging shelves in his dorm room. He accidentally hits his thumb with the hammer, which subsequently becomes swollen and red. He takes some aspirin for the pain. Many enzymes and other proteins are activated in response to injury leading to inflammation. Production of which of the following mediators is inhibited by aspirin?
Correct Answer: D
Rationale: Aspirin reduces inflammation from injury. PGE2 , a prostaglandin, is inhibited by aspirin's COX blockade. HAT , IκB , and NF-κB are unrelated. NO isn't primarily affected. PGE2's reduction explains aspirin's analgesic and anti-inflammatory effects.