ATI RN
ATI Pharmacology Practice A Questions
Question 1 of 5
The nurse plans to teach a class on anabolic steroids to a group of high school athletes. What will the best plan by the nurse include?
Correct Answer: A
Rationale: Anabolic steroids, synthetic testosterone derivatives, suppress natural hormone production, including spermatogenesis, leading to infertility-a critical risk for young athletes to understand. They also impact the entire body, notably causing liver damage (e.g., hepatotoxicity or tumors), a systemic effect worth noting. However, while effective for muscle growth, weight training surpasses steroids in safety and sustainability, debunking the ‘most effective' claim. Aggression, or ‘roid rage,' is a well-documented behavioral change due to hormonal imbalance, making it another key point. Infertility stands out in education, as it's a direct, long-term consequence tied to reproductive health, resonating with teens' future planning, and is supported by evidence of testicular atrophy and reduced sperm count, distinguishing it from broader effects or myths about efficacy.
Question 2 of 5
Amiodarone:
Correct Answer: B
Rationale: Amiodarone is a class III antiarrhythmic that affects sodium (Na+), potassium (K+), and calcium (Ca2+) channels, prolonging repolarization, so the statement excluding Ca2+ effects is false. It has antianginal effects by reducing myocardial oxygen demand through heart rate and afterload reduction, a true statement and its correct attribute. Its half-life is exceptionally long (weeks to months), not short, due to extensive tissue distribution, making that false. It decreases, not increases, peripheral resistance via vasodilation, so that's incorrect. It also affects the lungs, causing potential pulmonary toxicity, not minimal impact. The antianginal property is key to its use in angina alongside arrhythmias, reflecting its broad ion channel blockade and hemodynamic benefits, necessitating careful monitoring for side effects.
Question 3 of 5
When administering heparin subcutaneously, the nurse will follow which procedure?
Correct Answer: D
Rationale: When administering heparin subcutaneously, the nurse should use a - to -inch, 25- to 30-gauge needle to inject the medication into the subcutaneous tissue. This needle size is appropriate for delivering the medication effectively and safely in the subcutaneous layer rather than deeper into the muscle. Using the correct needle size helps ensure proper absorption and reduces the risk of complications such as bleeding or bruising at the injection site.
Question 4 of 5
Group of drugs which acts on amixed group of receptors:
Correct Answer: A
Rationale: Mixed agonist-antagonist drugs exhibit both agonistic and antagonistic properties at different receptor sites. These drugs can act as agonists at certain receptors while acting as antagonists at other receptors. This classification of drugs is distinct from pure agonists, pure antagonists, or partial agonists, as mixed agonist-antagonist drugs have a more complex mechanism of action. An example of a mixed agonist-antagonist drug is buprenorphine, which acts as a partial agonist at the mu opioid receptor and an antagonist at the kappa opioid receptor.
Question 5 of 5
A 40-year-old patient experiencing periods of mania and periods of depression would most likely benefit from which of the following?
Correct Answer: D
Rationale: Carbamazepine, a mood stabilizer, treats bipolar mania/depression-per psychiatry-unlike atomoxetine (ADHD), amitriptyline (depression), or methylphenidate (ADHD). It fits cycles, per evidence.