The nurse is teaching a patient how to self-administer triptan injections for migraine headaches. Which statement by the patient indicates that he needs further teaching?

Correct Answer: A

Rationale: Rationale: Choice A is incorrect because triptan injections are not meant for regular preventive use, but for acute treatment of migraine headaches when they occur. Taking the medication regularly for prevention goes against its intended use and can lead to overuse and potential side effects. Choices B, C, and D are correct as they align with the appropriate use of triptan injections for acute migraine treatment, accurate information about its effects, and monitoring the effectiveness of the treatment, respectively.

Correct Answer: D

Rationale: The correct answer is D because the patient's symptoms of vomiting, diarrhea, weakness, and extreme tiredness indicate severe dehydration and electrolyte imbalance, which can be dangerous. The nurse should advise the patient to come into the clinic for evaluation to assess his condition, rehydrate him, and check for any complications. This is crucial as the patient may need intravenous fluids and electrolyte replacement therapy. Choice A is incorrect because taking the diuretic with sips of water may not be sufficient to address the dehydration and electrolyte imbalance caused by the flu. Choice B is incorrect because stopping the diuretic abruptly can lead to further electrolyte imbalances and complications. Choice C is incorrect because increasing the dosage of the diuretic without evaluating the patient's condition could worsen the electrolyte imbalance and dehydration.

Correct Answer: C

Rationale: The correct answer is C: Fraction of an uncharged drug reaching the systemic circulation following any route administration. Bioavailability refers to the percentage of an administered drug that reaches the systemic circulation in an unchanged form. This definition excludes options A, B, and D as they do not directly relate to the concept of bioavailability. Plasma protein binding (A) refers to the extent to which a drug binds to proteins in the blood, brain-blood barrier permeability (B) is related to drug penetration into the brain, and the amount of a substance in urine relative to the initial dose (D) is more related to drug excretion rather than bioavailability. Thus, option C is correct as it specifically describes the concept of bioavailability.

Correct Answer: D

Rationale: The correct answer is D because all the substances listed interact with ion channels. Sodium channel blockers inhibit sodium influx, calcium channel blockers block calcium entry, and potassium channel activators enhance potassium efflux. A and B specifically target ion channels, while C indirectly influences ion channels through potassium activation. Therefore, all choices align with ion channel interactions.

Correct Answer: D

Rationale: The correct answer is D because the choice of a local anesthetic for specific procedures should consider multiple factors, including the duration of action (A), water solubility (B), and the capability of rapid penetration through the skin or mucosa with limited diffusion away from the site of application (C). Duration of action is important for ensuring adequate pain relief during the procedure, water solubility affects the onset of action and tissue penetration, and limited diffusion helps in maintaining the anesthetic effect at the target site. Therefore, considering all these factors collectively ensures the most appropriate choice of local anesthetic for a specific procedure. Choices A, B, and C on their own do not encompass all the essential considerations for selecting a local anesthetic, making them incorrect.