ATI RN
Intro to Pharmacology ATI Questions
Question 1 of 5
The nurse is reviewing the orders for a patient and notes a new order for an angiotensin-
Correct Answer: D
Rationale: Angiotensin-converting enzyme (ACE) inhibitors, a type of angiotensin inhibitor, may have a serious interaction with nonsteroidal anti-inflammatory drugs (NSAIDs). When used together, they may reduce the effectiveness of the ACE inhibitor in lowering blood pressure and could potentially lead to decreased kidney function. It is important for the nurse to be aware of this interaction and monitor the patient closely for any adverse effects when these medications are used concurrently.
Question 2 of 5
Combination chemotherapy is used in the treatment of cancer because:
Correct Answer: A
Rationale: Combination chemotherapy is used to target cancer cells through multiple mechanisms, reducing the likelihood of resistance. Single-agent therapy often leads to the development of resistant cell lines, as cancer cells can adapt to the drug. By using a combination of drugs with different mechanisms of action, the treatment can more effectively kill cancer cells and prevent resistance. While two drugs may increase efficacy, the primary rationale is to overcome resistance. Larger doses of single agents are not the main reason for combination therapy.
Question 3 of 5
The nurse is caring for a client receiving warfarin (Coumadin). Which instruction should the nurse include?
Correct Answer: A
Rationale: Warfarin's efficacy drops with high vitamin K intake, like spinach , risking clots'avoidance is key. Milk doesn't help. Stopping or doubling risks instability. Spinach avoidance aligns with warfarin's action, critical in anticoagulation where diet impacts INR, making A the essential instruction.
Question 4 of 5
The nurse is reviewing the orders for a patient and notes a new order for an angiotensin-
Correct Answer: D
Rationale: Angiotensin-converting enzyme (ACE) inhibitors, a type of angiotensin inhibitor, may have a serious interaction with nonsteroidal anti-inflammatory drugs (NSAIDs). When used together, they may reduce the effectiveness of the ACE inhibitor in lowering blood pressure and could potentially lead to decreased kidney function. It is important for the nurse to be aware of this interaction and monitor the patient closely for any adverse effects when these medications are used concurrently.
Question 5 of 5
The client receives nystatin (Nilstat) for a fungal infection in the mouth. The nurse plans to do medication education prior to discharge. What will the best plan by the nurse include?
Correct Answer: A
Rationale: Nystatin is an antifungal used for oral candidiasis (thrush), and its effectiveness depends on proper administration. For oral infections, the medication must remain in contact with the affected mucosal surfaces as long as possible. Dissolving the tablet in the mouth ensures prolonged exposure to the fungus, allowing it to act locally before swallowing, which is the recommended method for tablets or lozenges. Using a straw might apply to suspensions but isn't standard for preventing discoloration, which isn't a primary concern with nystatin. Crushing and mixing with juice alters the drug's intended delivery, reducing contact time with the infection site. Swallowing whole bypasses the oral mucosa entirely, rendering it ineffective for thrush. Thus, choice A aligns with nystatin's mechanism, ensuring optimal therapeutic outcomes through direct mucosal contact.