The nurse is reviewing factors that influence pharmacokinetics in the neonatal patient. Which factor puts the neonatal patient at risk with regard to drug therapy?

Correct Answer: A

Rationale: Neonates have an immature renal system, which affects the excretion of drugs and their metabolites. This immaturity can lead to prolonged drug half-lives and an increased risk of toxicity. While hyperperistalsis, irregular temperature regulation, and smaller circulatory capacity can influence drug therapy, the immature renal system is the most significant factor. Nurses must consider this when administering medications to neonates and adjust dosages accordingly to ensure safety and efficacy.

Correct Answer: C

Rationale: Pregnancy limits arthritis options-splinting supports joints safely, per non-drug care. Heat helps, not avoided. Hydroxychloroquine needs caution (Category C). Glucocorticoids (D) risk cleft palate-unsafe. Splinting fits pregnancy, per safety.

Correct Answer: B

Rationale: Sunscreen should provide protection against both UVA and UVB radiation and include SPF information (A). UVB radiation is most intense between 10 a.m. and 2 p.m. (B). An SPF of at least 15 is recommended (D). Clouds do not block all radiation, so sunscreen is still needed on cloudy days (C is incorrect).

Correct Answer: A

Rationale: Antihistamines target H1 receptors for allergy relief, not B1/B2 (choices B, C) or nonexistent C1 . A reflects their mechanism, making it correct.

Correct Answer: B

Rationale: Deadly nightshade (atropine) blocks muscarinic receptors. Decreased gastric acid secretion is correct-atropine inhibits parasympathetic stimulation of parietal cells. Bradycardia is wrong; tachycardia occurs. Increased bronchial secretions and salivation decrease, as does miosis (E)-pupils dilate. This anticholinergic effect explains the expected change in this poisoning.