ATI RN
Pharmacology Final ATI Quizlet Questions
Question 1 of 5
The nurse is preparing to administer heparin to a client. Which laboratory value should the nurse check prior to administration?
Correct Answer: B
Rationale: Heparin, an anticoagulant, prolongs clotting via antithrombin, monitored by aPTT to ensure therapeutic range (1.5-2.5 times normal) and prevent bleeding or clotting risks. PT/INR (choices A, C) track warfarin, not heparin. Platelet count matters for heparin-induced thrombocytopenia but isn't the primary pre-dose check'baseline and periodic counts suffice. aPTT directly reflects heparin's effect, guiding dosing adjustments, especially in acute settings like DVT or PE. Checking it ensures safety, as excessive anticoagulation causes hemorrhage, while under-dosing fails therapy. This aligns with heparin's rapid action and short half-life, making B the critical lab value to verify before administration.
Question 2 of 5
The ability of epinephrine to cause hyperglycemia is due to;
Correct Answer: C
Rationale: The ability of epinephrine to cause hyperglycemia is primarily due to its effect on alpha adrenoreceptors in the pancreatic islets of Langerhans. Epinephrine, acting through these alpha adrenoreceptors, inhibits the release of insulin from beta cells in response to elevated blood glucose levels. This results in decreased uptake of glucose by cells, leading to increased blood glucose levels, ultimately causing hyperglycemia. Other effects of epinephrine, such as vasoconstriction and increased heart rate, also contribute to the overall stress response, but the inhibition of insulin release through alpha adrenoreceptors is the main mechanism responsible for its hyperglycemic effects.
Question 3 of 5
Which of the following is an action of the drug Metformin?
Correct Answer: A
Rationale: Metformin is a commonly prescribed medication for the management of type 2 diabetes. One of the primary mechanisms of action of Metformin is to decrease hepatic glucose production. It works by inhibiting gluconeogenesis, which is the process by which the liver produces glucose. By reducing glucose production in the liver, Metformin helps to lower blood sugar levels and improve insulin sensitivity. This action helps to control hyperglycemia in patients with diabetes. The other options provided do not describe the mechanism of action of Metformin, making them incorrect choices.
Question 4 of 5
The following statements concerning renal drug handling are correct:
Correct Answer: B
Rationale: The kidneys filter approximately 130 mL/min of protein-free plasma, which is the glomerular filtration rate in healthy adults.
Question 5 of 5
When administering a standard or median effective dose to a patient, the nurse explains that this amount of drug will have which effect?
Correct Answer: C
Rationale: Median effective dose (ED50) affects 50% of a population, a statistical pharmacodynamic measure, not individual guarantee. No adverse effects isn't assured-safety varies. Metabolism timing depends on half-life, not ED50. Majority effectiveness exceeds 50%. Half the population defines ED50, explaining its intent.