The nurse is performing a genital examination on a male patient and notices urethral drainage. When collecting urethral discharge for microscopic examination and culture, the nurse should:

Correct Answer: D

Rationale: The correct answer is D because gently compressing the glans between the thumb and forefinger can help express the urethral discharge for collection. This method minimizes contamination and ensures a proper sample for microscopic examination and culture. A: Asking the patient to urinate into a cup would not capture the discharge. B: Semen is not relevant for urethral discharge testing. C: Inserting a cotton-tipped applicator into the urethra may cause trauma and is not recommended for collecting urethral discharge.

Correct Answer: D

Rationale: The correct answer is D: Ampicillin. Ampicillin is considered safe for use in newborn babies because it is a commonly used antibiotic in neonates and has a favorable safety profile. It is effective against a wide range of bacteria commonly found in newborns. Chloramphenicol (A) can cause serious side effects like gray baby syndrome. Trimethoprim/Sulfamethoxazole (B) is not recommended in newborns due to potential risks. Tetracyclines (C) can lead to tooth discoloration and bone growth inhibition in newborns.

Correct Answer: C

Rationale: The correct answer is C: Steven-Johnson syndrome from Trimethoprim/Sulfamethoxazole. Steven-Johnson syndrome is a severe and potentially life-threatening adverse reaction characterized by rash, blistering, and mucosal involvement. Once a patient experiences Steven-Johnson syndrome from a specific drug like Trimethoprim/Sulfamethoxazole, they should never be given that drug again due to the high risk of recurrence and the severity of the reaction. This is known as a contraindication, making it unsafe to administer the drug in the future. A, B, and D are incorrect because GI upset from Clarithromycin, skin rash from Ampicillin, and Clostridium difficile superinfection from Ciprofloxacin, while unpleasant, are not typically considered contraindications for future use of the same drug. These adverse reactions can often be managed with dose adjustments, alternative medications, or supportive care without ruling out the drug entirely

Correct Answer: A

Rationale: Step-by-step rationale: 1. Cloxacillin is a beta-lactam antibiotic effective against Staphylococci. 2. Streptococci are not within the spectrum of activity for Cloxacillin. 3. Gonococci are also not susceptible to Cloxacillin. 4. Therefore, the correct answer is A (Streptococci), as Cloxacillin is indicated only for Staphylococcal infections. Summary: Choice A is correct because Cloxacillin is effective against Staphylococci. Choices B and C are incorrect because Cloxacillin is not indicated for Gonococci or all of the organisms mentioned.

Correct Answer: C

Rationale: The correct answer is C: Trimethoprim/Sulfamethoxazole. This combination is the first-line treatment for Pneumocystis carinii pneumonia in patients with HIV-AIDS due to its efficacy against the organism. Trimethoprim inhibits bacterial folic acid synthesis, while sulfamethoxazole inhibits bacterial dihydrofolic acid formation. These drugs work synergistically to target different steps in the folic acid synthesis pathway of Pneumocystis carinii, leading to its effective eradication. Metronidazole (A) is used for anaerobic bacterial infections, Carbenicillin (B) is a penicillin derivative mainly used for Gram-negative bacteria, and Penicillin G (D) is not effective against Pneumocystis carinii.