The nurse is monitoring a post-renal transplantation client taking cyclosporine (Neoral). The nurse observes an elevation in one of the client's vital signs and the client is complaining of sweating and

Correct Answer: C

Rationale: Cyclosporine is an immunosuppressant medication commonly used in post-renal transplantation clients to prevent organ rejection. One of the common side effects of cyclosporine is hypertension, which can lead to an elevation in pulse rate. The increase in pulse rate is a compensatory mechanism by the body in response to increased blood pressure. Additionally, sweating can also be a side effect of cyclosporine, adding to the client's discomfort. Therefore, when a nurse observes an elevation in pulse rate along with sweating in a post-renal transplantation client taking cyclosporine, it is important to monitor closely for signs of hypertension and assess the need for further evaluation or intervention.

Correct Answer: A

Rationale: Cyclophosphamide in ALL risks hemorrhagic cystitis from acrolein, a toxic metabolite. Mesna binds acrolein, preventing bladder damage. Methylene blue , N-acetylcysteine , Ibuprofen , and Succimer (E) don't address this. Mesna's specificity ensures safe chemotherapy, critical in this young patient.

Correct Answer: C

Rationale: Warfarin is highly bioavailable (near 100%), so 90% is close and true. It doesn't inactivate vitamin K but inhibits vitamin K epoxide reductase, reducing clotting factor synthesis, making that false. It can paradoxically cause venous thrombosis (e.g., skin necrosis) early in therapy due to protein C depletion, a true statement. Initial loading is typically 5-10 mg, not 0.5 mg, so that's false. Metronidazole increases its effect via metabolism inhibition, not bactericidal action. The thrombosis risk is a rare but serious side effect, highlighting the need for bridging with heparin during initiation.

Correct Answer: C

Rationale: Lithium stabilizes mood but risks toxicity (e.g., >1.5 mEq/L), causing tremors , a neurologic sign needing reporting to adjust dosing or check levels. Thirst and weight gain are common, manageable. Nausea occurs but is less urgent unless severe. Tremors indicate potential overdose, critical in bipolar disorder where narrow therapeutic range demands vigilance, making C the key symptom to report.

Correct Answer: A

Rationale: A. Hypoglycemia is a major adverse effect of regular insulin. This occurs when insulin lowers blood glucose levels too much, causing symptoms such as sweating, shaking, confusion, and even loss of consciousness if severe.