ATI RN
ATI Pharmacology Exam Practice Questions
Question 1 of 5
The nurse is caring for a client receiving tamoxifen (Nolvadex) for breast cancer. Which side effect should the nurse monitor for?
Correct Answer: A
Rationale: Tamoxifen, an estrogen receptor modulator, treats breast cancer but blocks estrogen in some tissues, causing hot flashes , a common menopausal-like effect. Monitoring this ensures client comfort and adherence, as it's frequent and distressing. Hair loss is more chemotherapy-related, not tamoxifen. Nausea and diarrhea occur less often and are less specific. Hot flashes align with tamoxifen's anti-estrogenic action, a key consideration in breast cancer management where long-term use is common. This focus aids in symptom management, distinguishing it from cytotoxic effects, making A the priority side effect to monitor.
Question 2 of 5
A solution for the eyes
Correct Answer: D
Rationale: Collyria refers to eye drops or an eye lotion that is used to treat eye conditions. When the question is asking for a solution for the eyes, collyria is the most appropriate choice among the options given. Effervescent, mucilage, and spirits do not specifically relate to eye treatments. Collodion is a type of liquid adhesive used in medical settings, but it is not primarily intended for eye-related issues. Therefore, collyria is the correct solution for the eyes.
Question 3 of 5
Patients should avoid what drink while taking Alprazolam?
Correct Answer: B
Rationale: Patients taking Alprazolam should avoid consuming grapefruit juice. Grapefruit juice can interfere with the metabolism of Alprazolam in the body, leading to increased levels of the medication in the bloodstream. This can potentiate the sedative effects of Alprazolam and increase the risk of side effects or overdose. It is best to consult with a healthcare provider or pharmacist regarding any potential interactions with grapefruit juice and medications.
Question 4 of 5
Recent studies into the pathogenesis of halothane-induced malignant hyperthermia indicate which of the following as the likely implicating cause?
Correct Answer: B
Rationale: Malignant hyperthermia (MH) from halothane involves excitation-contraction coupling defects . MH, a genetic disorder, stems from ryanodine receptor (RYR1) mutations, causing uncontrolled calcium release in muscle, not drug toxicity . Sodium defects , oxygen deficits , or neural overmodulation (E) aren't implicated. This coupling defect triggers hypermetabolism, explaining MH's rapid onset with halothane exposure.
Question 5 of 5
A 55-year-old man with a 40 pack-year history of smoking develops agranulocytosis and some leukemic features. His physical examination of the heart, lungs, and abdomen are within normal limits. Should this disease relate to a potential toxic exposure, which of the following should be considered most likely?
Correct Answer: A
Rationale: Agranulocytosis and leukemic features in a smoker suggest benzene exposure. Benzene, in tobacco smoke, causes bone marrow toxicity. Ethylene alcohol , carbon tetrachloride , methanol , and toluene (E) don't link to leukemia. Benzene's carcinogenicity fits this profile.