The nurse is caring for a client receiving tamoxifen (Nolvadex) for breast cancer. Which side effect should the nurse monitor for?

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ATI Pharmacology Exam Practice Questions

Question 1 of 5

The nurse is caring for a client receiving tamoxifen (Nolvadex) for breast cancer. Which side effect should the nurse monitor for?

Correct Answer: A

Rationale: Tamoxifen, an estrogen receptor modulator, treats breast cancer but blocks estrogen in some tissues, causing hot flashes , a common menopausal-like effect. Monitoring this ensures client comfort and adherence, as it's frequent and distressing. Hair loss is more chemotherapy-related, not tamoxifen. Nausea and diarrhea occur less often and are less specific. Hot flashes align with tamoxifen's anti-estrogenic action, a key consideration in breast cancer management where long-term use is common. This focus aids in symptom management, distinguishing it from cytotoxic effects, making A the priority side effect to monitor.

Question 2 of 5

The following are first-line drugs for hypertension in diabetics with proteinuria:

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

When administering the drug senna to a patient, what must a health care provider inform the patient of?

Correct Answer: B

Rationale: The correct answer is B. Senna is a laxative used for short-term relief of constipation, not for long-term use. Choice A is incorrect because senna does not lower blood pressure or require combination with antihypertensives. Choice C is unrelated as there is no need to limit fiber intake with senna. Choice D is incorrect as orthostatic hypotension is not a common concern with senna use.

Question 4 of 5

What should you assess for in a patient who is on Valproate?

Correct Answer: A

Rationale: The correct answer is A: Suicidal thoughts. When a patient is prescribed Valproate, it is crucial to assess for suicidal thoughts as it is a serious side effect associated with this medication. Valproate has been linked to an increased risk of suicidal ideation and behavior, particularly in patients with epilepsy or bipolar disorder. Monitoring for signs of depression or changes in behavior is essential to ensure patient safety and well-being. Choices B, C, and D are incorrect because while monitoring for seizures, managing bipolar disorder, and treating migraines are also important considerations when a patient is on Valproate, assessing for suicidal thoughts takes priority due to the serious nature of this potential side effect.

Question 5 of 5

A patient has been taking hydrocodone, an opioid analgesic for their moderate pain, and they have taken more than the prescribed dose. What should you administer as the antidote if they experience toxicity?

Correct Answer: A

Rationale: Naloxone is the specific antidote for opioid toxicity. It works by blocking the effects of opioids on the central nervous system, thereby reversing symptoms like respiratory depression and sedation. N-acetylcysteine is used for acetaminophen overdose, while atropine is indicated for certain types of poisonings. Digoxin immune Fab is used for digoxin toxicity. Therefore, in the case of opioid toxicity due to hydrocodone overdose, naloxone is the appropriate antidote.

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