ATI RN
ATI Proctored Pharmacology 2023 Quizlet Questions
Question 1 of 5
The nurse is aware that efficient absorption of calcium is assisted by
Correct Answer: D
Rationale: Calcium absorption in the small intestine relies heavily on vitamin D, which enhances the process by increasing the expression of calcium-binding proteins and improving gut uptake efficiency. Without adequate vitamin D, calcium absorption drops significantly, leading to potential bone health issues like osteoporosis or osteomalacia. Intrinsic factor, produced in the stomach, is critical for vitamin B12 absorption, not calcium, as it binds B12 for uptake in the ileum. Coenzymes, while involved in metabolic reactions, don't directly facilitate calcium absorption; their role is broader and unrelated to this specific process. Phosphorus, an abundant mineral, works with calcium in bone formation but doesn't enhance its absorption-in fact, excessive phosphorus can compete with calcium. Vitamin D's active form, calcitriol, regulates calcium levels by promoting its transport across intestinal cells, making it indispensable for maintaining skeletal integrity. This mechanism underscores why vitamin D deficiency impairs calcium utilization, distinguishing it from the other options, which lack a direct link to absorption efficiency.
Question 2 of 5
A 25-year-old male comes to the emergency department with crushing, substernal chest pain. The pain radiates up to his jaw and down to his right arm. He has never had chest pain like this before. An ECG shows ST elevations in leads I, II, and AVF. A detailed history reveals that he had used cocaine 2 h prior to the onset of chest pain. Which of the following medications is contraindicated in the treatment of myocardial infarction caused by his cocaine use?
Correct Answer: C
Rationale: Cocaine-induced MI (ST elevations) contraindicates β-blockers . They exacerbate coronary vasospasm via unopposed α-stimulation. ACE inhibitors , aspirin , calcium channel blockers , and nitroglycerin (E) are safe. β-Blockers worsen this unique MI etiology.
Question 3 of 5
The nurse manages care for several clients receiving hormone replacement therapy (HRT). What will the priority assessment by the nurse include as related to side effects?
Correct Answer: A
Rationale: HRT, often involving estrogen, increases thrombophlebitis risk due to enhanced clotting factors. Calf pain signals possible deep vein thrombosis (DVT), a life-threatening side effect requiring immediate assessment, as it could lead to pulmonary embolism. Decreased libido , low-back pain , and fatigue may occur with HRT but are less urgent and not specific to its most dangerous complications. The nurse prioritizes calf pain due to its association with thromboembolism, a well-documented HRT risk, especially in smokers or those with vascular issues, making choice A the critical focus for safety.
Question 4 of 5
A patient has a digoxin level of 1.1 ng/mL. Which interpretation by the nurse is correct?
Correct Answer: A
Rationale: The therapeutic range for digoxin levels is typically between 0.8-2.0 ng/mL. A digoxin level of 1.1 ng/mL falls below the lower end of the therapeutic range, indicating that it is below the level considered effective for therapeutic benefits. Therefore, the correct interpretation by the nurse is that it is below the therapeutic level.
Question 5 of 5
A drug with a half life of 12 hours is administered by continuous intravenous infusion. How long will it take for the drug to reach 90% of its final steady-state level?
Correct Answer: C
Rationale: When a drug is administered by continuous intravenous infusion, it will take approximately 4-5 half-lives for it to reach 90% of its final steady-state level. In this case, the drug has a half-life of 12 hours, so it will take 4 half-lives (12 hours x 4 = 48 hours) for the drug to reach 90% of its final steady-state level. Therefore, the drug will reach 90% of its final steady-state level after 48 hours of continuous infusion.