ATI RN
Basic Principles of Pharmacology Quizlet Questions
Question 1 of 5
The nurse in the clinical research setting is knowledgeable about ethical principles and protection of human subjects. What principle is demonstrated by ensuring the patient’s right to self- determination?
Correct Answer: B
Rationale: The correct answer is B: Respect for persons. This principle is demonstrated by ensuring the patient's right to self-determination, which means respecting their autonomy and right to make decisions about their own healthcare. This principle is a fundamental aspect of research ethics, emphasizing the importance of treating individuals as autonomous agents. A: Beneficence focuses on doing good for the research subjects and maximizing benefits while minimizing harms, but it does not directly relate to self-determination. C: Justice involves fairness in the selection of research participants and distribution of benefits and burdens, but it is not directly related to self-determination. D: Informed consent is a process that includes providing information to participants to ensure they can make an informed decision about participating in research, which is related to but not the same as respecting self-determination.
Question 2 of 5
The nurse knows that the patient should be informed about the risks and benefits related to clinical research. What ethical principle does this describe?
Correct Answer: D
Rationale: The correct answer is D: Informed consent. Informed consent is a fundamental ethical principle in research that requires individuals to be fully informed about the risks and benefits before participating. This principle ensures that individuals can make autonomous decisions based on complete information. Respect for persons (A) is related but focuses more on treating individuals with dignity and autonomy. Justice (B) pertains to fair distribution of benefits and risks in research. Beneficence (C) is about maximizing benefits and minimizing harms for participants, which is important but not directly related to informing patients about risks and benefits.
Question 3 of 5
The patient has questions about counterfeit drugs. Which factors alert the patient or nurse that a drug is counterfeit or adulterated? (Select all that apply.)
Correct Answer: A
Rationale: The correct answer is A: Variations in packaging. Counterfeit drugs often have packaging that differs from the authentic product, such as misspelled labels or different colors. This alerts the patient or nurse to the possibility of counterfeit drugs. B: Unexpected side effects are not a reliable indicator of counterfeit drugs since legitimate drugs can also cause unexpected reactions. C: Oral drugs being dissolved through pinocytosis is a normal physiological process and not indicative of counterfeit drugs. D: Privacy of health information is unrelated to identifying counterfeit drugs.
Question 4 of 5
The nurse is explaining drug action to a nursing student. Which statement made by the nurse is correct?
Correct Answer: B
Rationale: B: A drug not bound to protein is an active drug. Rationale: Protein-bound drugs are inactive as they cannot reach target sites. When unbound, drugs can exert pharmacological effects. This is known as the free drug hypothesis. The statement correctly highlights the importance of drug binding to proteins in affecting drug action. Summary: A: Water-soluble and ionized drugs are slow to be absorbed due to their inability to cross membranes easily. C: Receptors are found on the cell membrane, not under it. This statement is inaccurate. D: Toxic effects are more likely to occur with high trough levels, not low levels.
Question 5 of 5
The nurse is meeting with a community group about medication safety. The nurse must emphasize that patients at high risk for drug interactions include which groups? (Select all that apply.)
Correct Answer: A
Rationale: The correct answer is A (Older patients) because elderly individuals tend to have multiple comorbidities and are more likely to be prescribed multiple medications, increasing the risk of drug interactions. Older patients also tend to have age-related physiological changes that can affect drug metabolism. Choice B (Patients with chronic health conditions) is not necessarily always at high risk for drug interactions, as it depends on the specific medications they are taking and their individual health status. Choice C (Patients taking three or more drugs) is not always a high-risk group, as drug interactions can occur even with fewer medications based on the specific drugs being taken and individual patient factors. Choice D (Patients dealing with only one pharmacy) is not directly related to the risk of drug interactions, as the number of pharmacies used by a patient does not necessarily correlate with the risk of drug interactions.