ATI RN
Immune System Drugs Questions
Question 1 of 5
The nurse has an order to administer oprelvekin (Neumega) to a patient for the first time. Before administering the drug, what allergy would the nurse want to specifically question the patient about?
Correct Answer: B
Rationale: The correct answer is B: Escherichia coli-produced products. Oprelvekin is a recombinant human interleukin-11 produced in Escherichia coli bacteria. Therefore, the nurse should specifically question the patient about any allergies to Escherichia coli-produced products before administering the drug. A: Egg products - Not relevant to oprelvekin. C: Lactose intolerance - Not relevant to oprelvekin. D: Penicillin - Not relevant to oprelvekin.
Question 2 of 5
A 70-year-old patient with acute myelocytic leukemia is receiving sargramostim (Leukine). What is a priority nursing action for this patient?
Correct Answer: B
Rationale: The correct answer is B: Increasing fluids. This is because sargramostim can cause fluid retention and capillary leak syndrome, leading to fluid overload. By increasing fluids, the nurse can help prevent complications such as pulmonary edema. Providing a quiet environment (A), comfort measures for nausea (C), and encouraging dietary intake (D) are important but not the priority in this case. Increasing fluids takes precedence due to the potential serious adverse effects of sargramostim.
Question 3 of 5
How do immune suppressants work when ordered for a patient who has had an organ transplant?
Correct Answer: A
Rationale: The correct answer is A because immune suppressants block the normal effects of the immune system in order to prevent rejection of the transplanted organ. By suppressing the immune response, the body is less likely to attack and reject the new organ. Choice B is incorrect because immune suppressants do the opposite of stimulating the immune system - they actually suppress it. Choice C is incorrect because immune suppressants do not work with corticosteroids to enhance healing. They work independently to suppress the immune response. Choice D is incorrect because immune suppressants do not work with corticosteroids to promote suppressor cells. Suppressors cells play a different role in the immune system compared to immune suppressants.
Question 4 of 5
The nurse admits a patient who was newly diagnosed with Kaposi's sarcoma to the unit. The physician has ordered an IV infusion of an interferon. What drug would be appropriate?
Correct Answer: C
Rationale: The correct answer is C: Interferon alfa 2b. Interferon alfa 2b is commonly used in the treatment of Kaposi's sarcoma. It has shown efficacy in inhibiting the growth of tumor cells and boosting the immune system. Interferon beta1a (A) is used for multiple sclerosis, not Kaposi's sarcoma. Interferon gamma 1b (B) is used for chronic granulomatous disease, not Kaposi's sarcoma. Peginterferon alfa 2b (D) is used for hepatitis C, not Kaposi's sarcoma. Hence, choice C is the most appropriate for this patient.
Question 5 of 5
What monoclonal antibody is used to prevent respiratory syncytial virus (RSV) in high-risk children?
Correct Answer: A
Rationale: The correct answer is A: Palivizumab. Palivizumab is used to prevent RSV in high-risk children by targeting the RSV F protein, reducing the severity of infection. Natalizumab (B) is used for multiple sclerosis, Belimumab (C) is for systemic lupus erythematosus, and Eculizumab (D) is for atypical hemolytic uremic syndrome, making them incorrect choices for preventing RSV.