ATI RN
Intro to Pharmacology ATI Questions
Question 1 of 5
The nurse frequently administers propranolol (Inderal) as treatment for what condition?
Correct Answer: B
Rationale: The beta-adrenergic blocking agents are used to treat cardiovascular problems (hypertension, angina, migraine headaches) and to prevent reinfarction after MI. The prototype drug, propranolol, was in fact the most prescribed drug in the country in the 1980s and is still considered a first-line drug. Propranolol does not prevent first MIs and it is not used for hypotension or cluster headaches. The nurse should understand the indications for propranolol to ensure safe and effective administration.
Question 2 of 5
Which of the following are possible mechanisms for the bactericidal/bacteriostatic effects of antiseptics and disinfectants?
Correct Answer: A
Rationale: Antiseptics and disinfectants exert their bactericidal/bacteriostatic effects through various mechanisms, including:
Question 3 of 5
The client receives nystatin (Nilstat) for a fungal infection in the mouth. The nurse plans to do medication education prior to discharge. What will the best plan by the nurse include?
Correct Answer: A
Rationale: Nystatin is an antifungal used for oral candidiasis (thrush), and its effectiveness depends on proper administration. For oral infections, the medication must remain in contact with the affected mucosal surfaces as long as possible. Dissolving the tablet in the mouth ensures prolonged exposure to the fungus, allowing it to act locally before swallowing, which is the recommended method for tablets or lozenges. Using a straw might apply to suspensions but isn't standard for preventing discoloration, which isn't a primary concern with nystatin. Crushing and mixing with juice alters the drug's intended delivery, reducing contact time with the infection site. Swallowing whole bypasses the oral mucosa entirely, rendering it ineffective for thrush. Thus, choice A aligns with nystatin's mechanism, ensuring optimal therapeutic outcomes through direct mucosal contact.
Question 4 of 5
The following drugs undergo phase II metabolism by hepatic acetylation enzymes (N-acetyltransferases):
Correct Answer: D
Rationale: Isoniazid undergoes phase II acetylation via hepatic N-acetyltransferases, and the rate of metabolism can vary between slow and fast acetylators.
Question 5 of 5
A patient comes to the hospital with a suspected opioid overdose, what would be the appropriate medication to be administered?
Correct Answer: B
Rationale: Naloxone is the appropriate medication to be administered to a patient with a suspected opioid overdose. Naloxone is an opioid receptor antagonist, meaning it can quickly reverse the effects of opioids on the central nervous system. It works by binding to the same receptors in the brain that opioids target, blocking their effects and rapidly restoring normal respiration and consciousness in a person who has overdosed on opioids. This can be a life-saving treatment for opioid overdose patients. Exenatide, Heparin, and Tolvaptan are not appropriate medications for reversing opioid overdose.