The most suitable vitamin D preparation for vitamin D dependent rickets is:

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Chapter 14 Drugs for the Reproductive System Questions

Question 1 of 5

The most suitable vitamin D preparation for vitamin D dependent rickets is:

Correct Answer: D

Rationale: The correct answer is D: Calcitriol. Calcitriol is the active form of vitamin D and is the most suitable preparation for vitamin D dependent rickets as it directly increases calcium absorption in the intestines and promotes bone mineralization. Calcitriol is essential for regulating calcium and phosphorus levels in the body. Choice A, Calciferol, is a general term for vitamin D compounds and is not specific enough for rickets treatment. Choice B, Cholecalciferol, is the precursor form of vitamin D and needs to be converted to calcitriol in the body. Choice C, Calcifediol, is an intermediate form that also requires conversion to calcitriol for biological activity. Therefore, calcitriol is the most appropriate choice for treating vitamin D dependent rickets due to its direct action on calcium metabolism and bone health.

Question 2 of 5

Actions of oxytocin include the following except:

Correct Answer: A

Rationale: 1. Oxytocin is a hormone that primarily functions in inducing uterine contractions and milk let-down. 2. Vasoconstriction is not a known physiological action of oxytocin. 3. Increased water reabsorption, mammary contraction, and prostaglandin release are all effects of oxytocin. 4. Therefore, the correct answer is A: Vasoconstriction, as it is not a typical action of oxytocin.

Question 3 of 5

Concurrent use of the following drug is likely to cause failure of oral contraception:

Correct Answer: B

Rationale: The correct answer is B: Rifampicin. Rifampicin is an enzyme inducer that can accelerate the metabolism of oral contraceptives, leading to decreased effectiveness and potential contraceptive failure. It induces hepatic enzymes, increasing the metabolism of estrogen and progestin in oral contraceptives, reducing their efficacy. Isoniazid (A), Cimetidine (C), and Propranolol (D) do not have significant interactions with oral contraceptives.

Question 4 of 5

The most common and important undesirable effect of injectable contraceptive depot medroxyprogesterone acetate is:

Correct Answer: B

Rationale: The correct answer is B: Disruption of cyclic menstrual bleeding. Injectable contraceptive depot medroxyprogesterone acetate can cause irregular menstrual bleeding patterns, such as prolonged spotting or amenorrhea. This occurs due to the suppression of ovulation and the thinning of the endometrial lining. Nausea and vomiting (choice A) are less common side effects and usually subside after the initial injections. Venous thrombosis (choice C) and hypertension (choice D) are more associated with combined hormonal contraceptives containing estrogen.

Question 5 of 5

The purpose/purposes served by the progestin component of the combined estrogen + progestin contraceptive pill is/are:

Correct Answer: D

Rationale: The correct answer is D because the progestin component of the combined pill serves multiple purposes. Firstly, it suppresses ovulation by inhibiting the release of an egg from the ovary, preventing pregnancy. Secondly, it helps induce prompt bleeding at the end of the pill course, mimicking a natural menstrual cycle. Lastly, progestin also blocks the increased risk of endometrial carcinoma associated with unopposed estrogen use. Therefore, all of the choices A, B, and C are correct in relation to the purposes served by the progestin component.

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