The most serious side effect of sulphonamides in neonates is:

Correct Answer: A

Rationale: Sulphonamides displace bilirubin from albumin in neonates, leading to kernicterus, a severe neurological condition.

Correct Answer: D

Rationale: Chloramphenicol is not used for tuberculosis, which requires specific drugs like isoniazid and rifampin.

Correct Answer: A

Rationale: First-generation cephalosporins (e.g., cefazolin) are relatively beta-lactamase resistant, unlike later generations with broader spectra.

Correct Answer: C

Rationale: Gentamicin causes nephrotoxicity and ototoxicity, not hemolytic anemia, which is not a typical side effect.

Correct Answer: D

Rationale: Ciprofloxacin is a systemic antibiotic, not a urinary antiseptic like the others, which act locally in the urinary tract.