The most important virulence factor of Neisseria meningitidis is:

Correct Answer: B

Rationale: The correct answer is B: Polysaccharide capsule. The capsule of Neisseria meningitidis is crucial for its virulence as it helps the bacteria evade the host immune system by inhibiting phagocytosis. This allows the bacteria to survive and multiply in the host, leading to invasive infections. Exotoxins, beta-lactamase, and pyrogenic toxins are not the main virulence factors of Neisseria meningitidis and do not play as significant a role in its pathogenicity as the polysaccharide capsule.

Correct Answer: A

Rationale: Step 1: Viruses can have either DNA or RNA, not both, hence they have only one type of nucleic acid. Step 2: The extracellular form of viruses is called virion, not viroid. Step 3: Viruses are obligate intracellular parasites, meaning they rely on host cells for replication. Step 4: Viruses are measured in nanometers, not micrometers. Therefore, the correct answer is A.

Correct Answer: A

Rationale: Polyclonal antibodies are produced by different B cells, each recognizing a different epitope on an antigen. Therefore, they can respond to multiple antigens. This diversity in recognition allows polyclonal antibodies to bind to various targets, making option A true. Options B, C, and D are incorrect as they do not accurately reflect the nature of polyclonal antibodies' ability to recognize multiple antigens.

Correct Answer: C

Rationale: The correct answer is C: Looking for Ernst-Babes granules. Laboratory diagnosis of rabies typically involves looking for Negri bodies in the brain tissue, intracerebrally infecting mice for virus isolation, and using immunofluorescence method to detect viral antigens. Ernst-Babes granules are not associated with rabies virus and are not used in the diagnosis of rabies. Therefore, choice C is incorrect.

Correct Answer: A

Rationale: Step-by-step rationale for choice A being correct: 1. Parvovirus B19 is a single-stranded DNA (ssDNA) virus. 2. The prefix "parvo-" indicates small size, characteristic of ssDNA viruses. 3. ssDNA viruses replicate in the host cell by converting their ssDNA genome into double-stranded DNA (dsDNA). 4. Therefore, the correct answer is A: Its genome consists of dsDNA. Summary of why other choices are incorrect: B: Parvovirus B19 is a non-enveloped virus, making choice B incorrect. C: Parvovirus B19 has a linear ssDNA genome, not segmented, making choice C incorrect. D: Parvovirus B19 has two structural proteins - VP1 and VP2, making choice D incorrect.