The MOST common cause of primary adrenal insufficiency in infancy is

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Pediatric Endocrine System Questions

Question 1 of 5

The MOST common cause of primary adrenal insufficiency in infancy is

Correct Answer: A

Rationale: Congenital adrenal hyperplasia (A), especially 21-hydroxylase deficiency, is the most common cause in infancy.

Question 2 of 5

Clinical manifestations of pheochromocytomas include the following EXCEPT

Correct Answer: D

Rationale: Obesity (D) is not a feature of pheochromocytomas; catecholamine excess causes weight loss.

Question 3 of 5

True gynecomastia is characterized by the presence of a palpable fibroglandular mass (located concentrically beneath the nipple and areolar region) at least

Correct Answer: D

Rationale: True gynecomastia requires a mass ≥2 cm (D) to distinguish from pseudogynecomastia.

Question 4 of 5

The 47,XXX (trisomy) chromosomal constitution is the most frequent extra-X chromosome abnormality in females, occurring in almost 1 in 1,000 liveborn females. It is characterized by the following EXCEPT

Correct Answer: C

Rationale: 47,XXX females typically have normal sexual development (not delayed, C).

Question 5 of 5

The following factors are implicated in the pathogenesis of type 1 DM EXCEPT

Correct Answer: D

Rationale: Excessive infection exposure (D) is not a risk factor; limited exposure may increase autoimmunity risk.

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