The MOST common cause of permanent congenital hypothyroidism is

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Endocrine System in Pediatrics Questions

Question 1 of 5

The MOST common cause of permanent congenital hypothyroidism is

Correct Answer: B

Rationale: Thyroid dysgenesis (B) accounts for 80-85% of congenital hypothyroidism cases.

Question 2 of 5

Thyroid peroxidase antibodies are absent in the following thyroiditis syndrome

Correct Answer: C

Rationale: Painful subacute thyroiditis (C) is typically viral, not autoimmune, so TPO antibodies are absent.

Question 3 of 5

Aplasia or hypoplasia of the parathyroid glands is often associated with the DiGeorge/velocardiofacial syndrome. All the following regarding this syndrome are true EXCEPT

Correct Answer: D

Rationale: Hypocalcemia in DiGeorge syndrome is usually neonatal and transient (C), not typically delayed (D).

Question 4 of 5

The MOST consistent and characteristic radiographic finding of primary hyperparathyroidism is

Correct Answer: D

Rationale: Subperiosteal bone resorption (D) is the hallmark radiographic sign of primary hyperparathyroidism.

Question 5 of 5

The clinical presentation of adrenal insufficiency depends on the age of the patient, the usual presentation of adrenal insufficiency in infancy is

Correct Answer: D

Rationale: Hypoglycemia (D) is a hallmark of adrenal insufficiency in infants due to cortisol deficiency.

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