The MOST common cardiac defect in Noonan syndrome is

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Endocrine System in Pediatrics Questions

Question 1 of 5

The MOST common cardiac defect in Noonan syndrome is

Correct Answer: B

Rationale: Pulmonary valvular stenosis (B) is the most common cardiac defect in Noonan syndrome.

Question 2 of 5

Cerebral edema complicating DKA remains the major cause of morbidity and mortality in children and adolescents with T1 DM. All the following are true EXCEPT

Correct Answer: D

Rationale: Radiographic imaging (D) is not frequently helpful; cerebral edema is often a clinical diagnosis.

Question 3 of 5

Transient elevation of urinary albumin can occur in the following conditions EXCEPT

Correct Answer: A

Rationale: Hypoglycemia (A) does not typically elevate urinary albumin; others (B-E) do.

Question 4 of 5

Therapy with one of the following drugs usually results in significant insulin resistance leading to glucose intolerance and overt diabetes

Correct Answer: C

Rationale: High-dose steroids (C) commonly cause insulin resistance and diabetes.

Question 5 of 5

A 3-year-old boy presented with history of hyperactivity and mild mental retardation. Past history revealed repeated projectile vomiting with normal abdominal sonography. On examination, there are eczematoid rash with lighter skin, microcephaly, and mild spasticity with exaggerated tendon reflexes. Of the following, the MOST likely urine odor of this baby is

Correct Answer: A

Rationale: Phenylketonuria (PKU) matches this presentation (mental retardation, rash, spasticity, vomiting) and produces a musty urine odor due to phenylacetate, unlike other odors linked to different disorders (B, C, D, E).

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