ATI RN
Pediatric Immune Disorder Test Questions Questions
Question 1 of 5
The MOST appropriate method to correct the immune deficiency in complete DiGeorge syndrome is
Correct Answer: D
Rationale: Complete DiGeorge syndrome lacks T-cell function due to absent thymus; thymic transplantation restores T-cell immunity, addressing the root cause.
Question 2 of 5
Leukemoid reactions (WBC count >50,000/μL) are caused by all the following EXCEPT
Correct Answer: D
Rationale: Chronic granulomatous disease causes defective neutrophil function, not leukemoid reactions, which are triggered by severe infections like shigellosis.
Question 3 of 5
All the following matching about genetic deficiencies of plasma complement components and associated clinical findings are true EXCEPT
Correct Answer: A
Rationale: C4 deficiency is more strongly linked to systemic lupus erythematosus than discoid lupus, making this pairing less accurate.
Question 4 of 5
How are B-cell and T-cell antigen receptors distributed?
Correct Answer: C
Rationale: B and T cell receptors are distributed clonally, meaning each lymphocyte expresses a unique receptor specific to an antigen, expanded upon activation.
Question 5 of 5
Which of the following components of the adaptive immune system causes lysis of virally infected cells and the release of cytokines?
Correct Answer: C
Rationale: CD8+ cytotoxic T cells (CTLs) lyse virally infected cells and release cytokines to eliminate intracellular pathogens.