ATI RN
How to Study for ATI Pharmacology Proctored Exam Questions
Question 1 of 5
The metabolism of the drug en route from the gut lumen to the systemic circulation.
Correct Answer: B
Rationale: The first pass effect refers to the metabolism of a drug as it passes through the liver before reaching the systemic circulation. When a drug is absorbed from the gut lumen, it first enters the portal circulation where it is transported to the liver. In the liver, the drug may undergo metabolic processes that can reduce the amount of active drug reaching systemic circulation. This process can greatly affect the overall bioavailability and effectiveness of the drug. So, the metabolism of the drug en route from the gut lumen to the systemic circulation is primarily due to the first pass effect.
Question 2 of 5
An international traveler diagnosed with malaria is admitted to the emergency department and is prescribed mefloquine hydrochloride. The nurse anticipates that which laboratory test will be ordered?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
What agents are used primarily to treat cardiac-related conditions? (Select all that apply.)
Correct Answer: B
Rationale: Drugs that block both alpha- and beta-adrenergic receptors are primarily used to treat cardiac-related conditions. Phentolamine, a nonselective alpha-adrenergic blocking agent, is used to treat extravasation of IV norepinephrine or dopamine and hypertension related to a pheochromocytoma. Alpha1-selective adrenergic blocking agents are used for treatment of hypertension and benign prostatic hyperplasia. The beta-adrenergic blocking agents are used to treat cardiovascular problems (hypertension, angina, migraine headaches) and to prevent reinfarction after myocardial infarction. Beta1-selective adrenergic blocking agents are used for treating hypertension, angina, and some cardiac arrhythmias. The nurse should understand the indications for these agents to ensure safe and effective administration.
Question 4 of 5
A patient has an order for metoprolol. Prior to medication administration, what does the nurse need to assess?
Correct Answer: C
Rationale: Metoprolol, a beta-blocker, can cause bradycardia. The nurse must assess the patient’s heart rate before administration to ensure it is within a safe range (typically >60 beats/minute). Respirations (A), temperature (B), and oxygen saturation (D) are less critical for metoprolol administration.
Question 5 of 5
A client who is taking Methotrexate (Trexall) asks the nurse on what is the appropriate activity while taking the medication. The nurse advised the client to play which activity?
Correct Answer: D
Rationale: Tennis is a low-impact activity that is generally safe for patients on methotrexate, as it minimizes the risk of injury and bleeding. High-impact or contact sports like basketball, ice hockey, and football are discouraged due to the increased risk of trauma and bleeding, especially since methotrexate can cause myelosuppression. Encouraging safe physical activity is important for overall health, but precautions must be taken to avoid complications.