The mechanism of action of carbamazepine appears to be similar to that of:

Questions 52

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Drugs Affecting Cardiovascular System Questions

Question 1 of 5

The mechanism of action of carbamazepine appears to be similar to that of:

Correct Answer: C

Rationale: Carbamazepine is an antiepileptic drug that acts by blocking voltage-gated sodium channels, similar to Phenytoin. Both drugs inhibit sustained high-frequency repetitive firing of action potentials in neurons. Benzodiazepines (A) enhance inhibitory neurotransmission via GABA receptors, Valproate (B) inhibits GABA transaminase and increases GABA levels, and Ethosuximide (D) blocks T-type calcium channels, making them incorrect choices.

Question 2 of 5

Which of the following opioid analgesics is a partial mu receptor agonist?

Correct Answer: C

Rationale: Buprenorphine is a partial mu receptor agonist, meaning it activates the mu receptors but to a lesser extent compared to full agonists like morphine. Buprenorphine's unique pharmacological profile includes partial agonist activity at mu receptors, along with antagonist activity at kappa receptors. This combination results in a ceiling effect on respiratory depression and a lower risk of abuse potential compared to full agonists. Methadone is a full mu receptor agonist, morphine is a full mu receptor agonist, and sufentanyl is a potent full mu receptor agonist but is not a partial agonist like buprenorphine.

Question 3 of 5

Indicate the atypical antipsychotic drug:

Correct Answer: B

Rationale: The correct answer is B: Clozapine. Clozapine is considered an atypical antipsychotic due to its unique mechanism of action targeting serotonin and dopamine receptors. It is commonly used for treatment-resistant schizophrenia. Haloperidol (A) is a typical antipsychotic. Thioridazine (C) and Thiothixene (D) are also typical antipsychotics. They primarily target dopamine receptors and are associated with more side effects compared to atypical antipsychotics like Clozapine.

Question 4 of 5

Which of the following autonomic nervous system effects is common for tricyclic antidepressants?

Correct Answer: D

Rationale: The correct answer is D: All of the above. Tricyclic antidepressants like Amitriptyline have all three effects. Antimuscarinic action leads to dry mouth, constipation. Antihistaminic action causes sedation. Alpha adrenoreceptor-blocking action results in orthostatic hypotension. These side effects are common with tricyclic antidepressants due to their pharmacological properties.

Question 5 of 5

Which of the following CNS stimulants is used for the cerebral stroke treatment?

Correct Answer: C

Rationale: The correct answer is C: Piracetam. Piracetam is a nootropic agent that has shown potential in improving cognitive functions and enhancing cerebral blood flow, making it beneficial for cerebral stroke treatment. Pantocrin (A) is a general stimulant, Sydnocarb (B) is primarily used for ADHD and narcolepsy, and Caffeine (D) is a CNS stimulant but lacks specific benefits for cerebral stroke treatment. In summary, Piracetam is the correct choice due to its specific effects on cerebral function and blood flow, while the other options are not tailored for stroke treatment.

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