The mechanism of action of barbiturates differs from that of benzodiazepines in that they

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Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions

Question 1 of 5

The mechanism of action of barbiturates differs from that of benzodiazepines in that they

Correct Answer: D

Rationale: Barbiturates directly mimic GABA at high doses and enhance its action at lower doses unlike benzodiazepines.

Question 2 of 5

A 21-year-old male has recently begun pimozide therapy for Tourette's disorder. His parents bring him to the emergency department. They describe that he has been having “different appearing tics” than before, such as prolonged contraction of the facial muscles. While being examined, he experiences opsichotomus (type of extrapyramidal spasm of the body in which the head and heels are bent backward and the body is bowed forward). Which of the following drugs would be beneficial in reducing these symptoms?

Correct Answer: A

Rationale: Benztropine, an anticholinergic agent, is used to treat extrapyramidal symptoms like dystonia caused by antipsychotic medications.

Question 3 of 5

The neurotransmitter system in the brain most affected in Alzheimer's disease is

Correct Answer: D

Rationale: Alzheimer's disease is associated with cholinergic neuron degeneration.

Question 4 of 5

Digoxin affords the following benefit(s) in CHF

Correct Answer: D

Rationale: Digoxin improves symptoms but does not prolong survival in CHF.

Question 5 of 5

Following is used in methanol poisoning

Correct Answer: C

Rationale: Ethanol competes with methanol for alcohol dehydrogenase preventing the formation of toxic metabolites.

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