ATI RN
Safety Pharmacology Across the Lifespan Questions
Question 1 of 5
The mechanism of action of antiseizure drugs is:
Correct Answer: D
Rationale: Antiseizure drugs work through multiple mechanisms to reduce neuronal excitability and prevent seizures. Enhancement of GABAergic transmission increases inhibition, diminution of excitatory glutamatergic transmission reduces overstimulation, and modification of ionic conductance (e.g., sodium or calcium channels) stabilizes neuronal membranes. Since all these mechanisms are employed by various antiseizure drugs, the correct answer is 'all of the above.'
Question 2 of 5
Indicate an irreversible inhibitor of GABA aminotransferase (GABA-T):
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
A long-acting drug against both absence and myoclonic seizures is:
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Indicate a peripheral dopa decarboxylase inhibitor:
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Indicate a selective inhibitor of monoamine oxidase B:
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.