ATI RN
Quizlet WVU Pharmacology Cardiovascular Drugs Questions
Question 1 of 5
The major synthetic estrogens are following EXCEPT:
Correct Answer: D
Rationale: Rationale: The major synthetic estrogens are Dienestrol, Diethylstilbestrol, and Benzestrol, but not Estradiol. Estradiol is a natural estrogen produced by the ovaries. Therefore, D is the correct answer. Dienestrol, Diethylstilbestrol, and Benzestrol are synthetic estrogens used in hormone replacement therapy.
Question 2 of 5
Half-life of OKT-3 is:
Correct Answer: A
Rationale: The correct answer is A: 18-24 hours. The half-life of a drug is the time it takes for half of the drug to be removed from the body. OKT-3 has a relatively short half-life, typically ranging from 18 to 24 hours. This means that after 18-24 hours, only half of the initial dose of OKT-3 will remain in the body. Choice B (25-35 minutes) is too short for a drug like OKT-3 which is used for immunosuppression and requires a longer duration of action. Choice C (4-16 hours) falls within the correct range but is not as specific as the 18-24 hours range. Choice D (21 days) is too long for OKT-3, as drugs with such long half-lives are typically not used for immunosuppression due to the difficulty in adjusting dosages.
Question 3 of 5
Which of the following antivitamins prevent a vitamin B6 from exerting its typical metabolic effects?
Correct Answer: D
Rationale: The correct answer is D: All of the above. Isoniazide, ethanol, and carbamazepine are all antivitamins that interfere with the metabolism of vitamin B6. Isoniazide inhibits the conversion of vitamin B6 to its active form, ethanol decreases the absorption and utilization of vitamin B6, and carbamazepine reduces the plasma levels of vitamin B6. Therefore, all three choices prevent vitamin B6 from exerting its metabolic effects. The other choices are incorrect because each of them individually interferes with the action of vitamin B6.
Question 4 of 5
The bile acid-binding resins can bind many drugs and vitamins and reduce their absorption. This consideration is:
Correct Answer: A
Rationale: The correct answer is A: TRUE. Bile acid-binding resins can bind to various drugs and vitamins in the gastrointestinal tract, leading to reduced absorption. This occurs due to the resins' ability to form complexes with these substances, preventing their uptake into the bloodstream. This interference can potentially impact the effectiveness of medications or the absorption of essential vitamins. Choices B, C, and D are incorrect because they do not accurately reflect the specific mechanism of action of bile acid-binding resins in drug and vitamin absorption.
Question 5 of 5
Side effect of dihydrotachysterol is:
Correct Answer: A
Rationale: The correct answer is A: Hepatic toxicity. Dihydrotachysterol is a vitamin D analog used to treat hypoparathyroidism and hypocalcemia. It can cause liver damage as a side effect due to its metabolism in the liver. General malaise (B), lymphocytopenia (C), and hypertension (D) are not typically associated with dihydrotachysterol use. Therefore, the correct answer is A based on the drug's mechanism of action and known side effects.