The major mineralocorticoids are the following, EXCEPT:

Correct Answer: D

Rationale: The correct answer is D: Hydrocortisone, as it is a glucocorticoid, not a mineralocorticoid. Mineralocorticoids regulate electrolyte and fluid balance, primarily aldosterone, deoxycorticosterone, and fludrocortisone. Hydrocortisone primarily functions as a glucocorticoid to regulate metabolism and immune response, not electrolyte balance.

Correct Answer: D

Rationale: Resorptive sulfonamides are known to cause hematological adverse effects. Hemolytic anemia occurs due to the destruction of red blood cells, thrombocytopenia is a decrease in platelet count leading to bleeding disorders, and granulocytopenia is a reduction in granulocyte count affecting immunity. Therefore, all of the above choices (A, B, and C) are correct as resorptive sulfonamides can lead to hemolytic anemia, thrombocytopenia, and granulocytopenia. These adverse effects are well-documented in literature and clinical practice.

Correct Answer: A

Rationale: The correct answer is A: Levamisole. Levamisole blocks acetylcholine transmission at the myoneural junction of helminthes by inhibiting cholinesterase enzyme. This leads to paralysis and expulsion of the parasites from the host. Mebendazole (B) works by inhibiting microtubule synthesis in helminthes. Piperazine (C) causes paralysis by hyperpolarizing the helminth's muscle cells. Niclosamide (D) disrupts the helminth's energy metabolism. Therefore, Levamisole is the correct choice for blocking acetylcholine transmission specifically.

Correct Answer: B

Rationale: The correct answer is B: Cisplatin. Cisplatin is an anticancer drug belonging to inorganic metal complexes. It contains the metal platinum, which forms coordination complexes that interfere with DNA repair mechanisms in cancer cells, leading to cell death. Dacarbazine (A) is an organic compound, not an inorganic metal complex. Methotrexate (C) is a folate antagonist and Vincristine (D) is a vinca alkaloid, both are organic compounds unrelated to inorganic metal complexes. Thus, B is the correct choice for an anticancer drug belonging to inorganic metal complexes.

Correct Answer: B

Rationale: The correct answer is B: Adenosine. Adenosine is commonly used for treating supraventricular tachycardias, which can cause palpitations. It works by slowing electrical conduction in the heart, helping to restore normal heart rhythm. Mexiletine (A) is a sodium channel blocker used for ventricular arrhythmias. Sotalol (C) is a beta-blocker used for atrial and ventricular arrhythmias. Verapamil (D) is a calcium channel blocker used for atrial arrhythmias but not typically for palpitations due to supraventricular tachycardias.