The major cause of neonatal mortality in preterm infant is

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Nursing Practice Questions for Pediatric Infectious Disease Questions

Question 1 of 5

The major cause of neonatal mortality in preterm infant is

Correct Answer: C

Rationale: Respiratory distress syndrome (RDS, C) is the leading cause of death in preterm infants due to surfactant deficiency, outranking trauma (A), asphyxia (B), meconium aspiration (D), or PPHN (E).

Question 2 of 5

Neonatal hypocalcemia is considered when serum ionized calcium level is

Correct Answer: A

Rationale: Neonatal hypocalcemia is defined as ionized calcium ≤3.5 mg/dL (A), critical for neuromuscular function, per neonatal standards.

Question 3 of 5

A 3-month-old infant present with history of low birth weight, early-onset jaundice, and seizures; on examination there are hepatosplenomegaly and hydrocephalus; skull films reveal diffuse cortical calcifications. Of the following, the primary method of diagnosis is

Correct Answer: D

Rationale: Congenital infection (likely toxoplasmosis) with jaundice, hepatosplenomegaly, and calcifications is best diagnosed by serology (D, IgM/IgG), more definitive than PCR (A), culture (B), CT (C), or CSF (E) alone.

Question 4 of 5

The MOST common congenital infection and the leading cause of sensorineural hearing loss is

Correct Answer: C

Rationale: CMV (C) is the most prevalent congenital infection and top cause of sensorineural hearing loss, affecting ~1% of newborns, per CDC data.

Question 5 of 5

The treatment of choice for neonatal herpes simplex virus (HSV) infections is

Correct Answer: C

Rationale: Acyclovir (C) is the standard treatment for neonatal HSV, reducing morbidity and mortality, unlike observation (A), vaccination (B, none exists), IVIG (D), or ganciclovir (E, for CMV).

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