The main reason behind gamma irradiation of the blood products is to prevent

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Hematology Final Exam Questions Pdf Questions

Question 1 of 5

The main reason behind gamma irradiation of the blood products is to prevent

Correct Answer: C

Rationale: Gamma irradiation (C) inactivates lymphocytes in blood products, preventing GVHD in immunocompromised recipients, unlike bacterial (A), viral (B), allergic (D), or TRALI (E) risks.

Question 2 of 5

Vitamin K-dependent clotting factors include all the following EXCEPT

Correct Answer: A

Rationale: Vitamin K-dependent factors are II (B), VII (C), IX (D), and protein S (E). Factor I (A, fibrinogen) is not vitamin K-dependent.

Question 3 of 5

Lupus anticoagulants usually affect the following laboratory test

Correct Answer: B

Rationale: Lupus anticoagulants prolong PTT (B) by interfering with phospholipid-dependent clotting, not BT (A), PT (C), TT (D), or clot solubility (E).

Question 4 of 5

You are evaluating a 5-year-old male child with multiple ecchymoses distributed all over the extremities and trunk; examination reveal a palpable spleen $3 \mathrm{~cm}$ below the left costal margin. Lab findings include: hemoglobin, 11.3 g/dL; white blood cell count, 8700/mm3; platelets count, 21000/mm3. Of the following, the most proper NEXT step is

Correct Answer: D

Rationale: Thrombocytopenia (21,000/mm3) with splenomegaly suggests hypersplenism or marrow disorder. Bone marrow study (E) distinguishes production vs. sequestration, more definitive than BT (A), coagulation (B), aggregation (C), or US (D) initially.

Question 5 of 5

Microthrombocytes are MOST likely to be seen in

Correct Answer: C

Rationale: WAS (C) features small (micro) platelets due to cytoskeletal defects, unlike ITP (A, large), Bernard-Soulier (B, giant), Glanzmann’s (D), or type 2B vWD (E).

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