The least common presentation of acute intermittent porphyria is

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Pediatric Endocrine System Questions

Question 1 of 4

The least common presentation of acute intermittent porphyria is

Correct Answer: A

Rationale: Sensory loss (A) is less common in AIP than mental symptoms (B), weakness (C), abdominal pain (D), or extremity pain (E), which dominate acute attacks.

Question 2 of 4

All the following are secondary causes of hypercholesterolemia EXCEPT

Correct Answer: D

Rationale: Obesity (A), cholestasis (B), hypothyroidism (C), and nephrotic syndrome (E) raise cholesterol. Anorexia nervosa (D) typically lowers it due to malnutrition.

Question 3 of 4

All the following are clinical abnormalities of Zellweger syndrome EXCEPT

Correct Answer: D

Rationale: Zellweger syndrome features cataracts (A), micrognathia (B), high forehead (C), and neck folds (E). Small fontanels (D) contradict its wide fontanel characteristic.

Question 4 of 4

The MOST common presentation of mitochondrial β-oxidation of fatty acids disorders is

Correct Answer: D

Rationale: Fatty acid oxidation disorders (e.g., MCAD) most commonly present with hypoglycemic coma from fasting stress, more frequent than cardiomyopathy (A), weakness (B), tubulopathy (C), or rhabdomyolysis (E).

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