The irreversible MAO inhibitors have a very high risk of developing:

Correct Answer: C

Rationale: The correct answer is C. Irreversible MAO inhibitors can lead to hypertensive reactions due to tyramine buildup from food. MAO breaks down tyramine, so inhibition leads to excess tyramine causing dangerous spikes in blood pressure. Respiratory depression (A) and agranulocytosis (D) are not typically associated with MAO inhibitors. While cardiovascular collapse and CNS depression (B) can occur, the high risk is specifically for hypertensive crises due to tyramine interactions.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Cocaine, amphetamine, and caffeine are all stimulant drugs that affect the central nervous system, leading to increased alertness, energy, and euphoria. Cocaine is a powerful stimulant derived from the coca plant, amphetamine is a synthetic stimulant commonly used as a prescription medication or illicit drug, and caffeine is a naturally occurring stimulant found in coffee, tea, and other beverages. All three substances have similar effects on the body, making them related to stimulants. Therefore, the correct answer is D as all the options (A, B, and C) are related to stimulants.

Correct Answer: B

Rationale: Step 1: Chymotrypsin is a protease enzyme, not an agent containing free sulfhydryl groups. Step 2: Protease enzymes like chymotrypsin contain amino acids in their active site, not sulfhydryl groups. Step 3: Therefore, the statement that chymotrypsin is an agent containing free sulfhydryl groups is FALSE. Summary: Choice B is correct because chymotrypsin does not contain free sulfhydryl groups. Choices A, C, and D are incorrect because they do not accurately reflect the nature of chymotrypsin.

Correct Answer: C

Rationale: The correct answer is C: Loperamide. Loperamide is an antidiarrheal medication that works by slowing down gut motility and inhibiting peristalsis in the intestines. This helps to increase the absorption of water and electrolytes, leading to firmer stools. Castor oil (A) and Sorbitol (D) are laxatives that promote peristalsis and bowel movements. Bisacodyl (B) is a stimulant laxative that increases intestinal motility and promotes bowel movements. Therefore, choices A, B, and D are incorrect as they have the opposite effect of inhibiting peristalsis.

Correct Answer: D

Rationale: The correct answer is D because glycosides intoxication can lead to a variety of manifestations affecting different systems. Visual changes may occur due to the effects on the central nervous system. Ventricular tachyarrhythmias can result from the cardiac toxicity of glycosides. Gastrointestinal disturbances are also common, such as nausea, vomiting, and diarrhea. Therefore, all the above choices are correct manifestations of glycosides intoxication. Options A, B, and C are incorrect individually as they only represent some of the possible manifestations, whereas option D encompasses all the correct manifestations.