ATI RN
Pediatric Immunizations NCLEX Questions Questions
Question 1 of 5
The invariant chain the empty peptide-binding groove. After vesicle fusion, the invariant chain is and peptides can enter the MHC class II grove.
Correct Answer: D
Rationale: The invariant chain blocks the MHC Class II groove to prevent premature peptide binding and is degraded after vesicle fusion to allow peptide loading.
Question 2 of 5
Which of the following are pluripotential, self-renewing CD34+ cells?
Correct Answer: A
Rationale: HSCs are pluripotent, self-renewing, and express CD34.
Question 3 of 5
Granulocyte colony-stimulating factor (G-CSF) causes an increase in the production of which of the following in the bone marrow?
Correct Answer: A
Rationale: G-CSF specifically increases neutrophil production.
Question 4 of 5
Cortex
Correct Answer: A
Rationale: The cortex contains B cell follicles.
Question 5 of 5
During B cell development, negative selection occurs in an attempt to ensure the antigen receptor:
Correct Answer: D
Rationale: Negative selection eliminates B cells that bind self-antigens to prevent autoimmunity.