The integrin LFA-1 is constitutively expressed on the surface of resting T cells. Yet, integrin-dependent T cell adhesion to antigen-presenting cells increases substantially following TCR stimulation. This increased integrin-dependent adhesion is mediated in part by:

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Lymphatic System Review Questions Questions

Question 1 of 5

The integrin LFA-1 is constitutively expressed on the surface of resting T cells. Yet, integrin-dependent T cell adhesion to antigen-presenting cells increases substantially following TCR stimulation. This increased integrin-dependent adhesion is mediated in part by:

Correct Answer: C

Rationale: TCR signaling shifts LFA-1 to high affinity ; not synthesis , transport , or just phosphorylation .

Question 2 of 5

Which of the following statements about antibodies is false?

Correct Answer: D

Rationale: Mammalian antibodies have five classes (IgM, IgG, IgA, IgE, IgD), not two, making D false; others are true.

Question 3 of 5

Which of the following statements is true for antimicrobial peptides (AMPs)?

Correct Answer: C

Rationale: AMPs primarily perforate bacterial membranes to cause lysis, targeting prokaryotes, not enhancing phagocytosis or binding eukaryotic membranes.

Question 4 of 5

Complete this sentence. Major histocompatability complex type I (MHC)

Correct Answer: B

Rationale: MHC1 is on all nucleated cells, presenting processed peptides (8-10 aa) to CD8+ T cells, not CD4+.

Question 5 of 5

During negative selection, a strong interaction between an immature T cell receptor and self-peptide:

Correct Answer: D

Rationale: Strong binding triggers apoptosis to eliminate autoreactive T cells, not rescue or migration.

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