The innate immune system is always working to protect the body and does not require any special preparation to stop infection:

Correct Answer: A

Rationale: The correct answer is A: TRUE. The innate immune system is the body's first line of defense against infections and is always active, providing immediate protection without prior exposure to a specific pathogen. It includes physical barriers, such as skin and mucous membranes, and cellular components like phagocytes and natural killer cells. The innate immune response is nonspecific and rapid, providing a crucial initial defense against pathogens. Choice B is incorrect because the innate immune system is always active, even without any prior exposure to pathogens. Choice C is incorrect because the innate immune system is consistently functioning to protect the body, regardless of the situation. Choice D is incorrect as the correct answer is A.

Correct Answer: B

Rationale: The correct answer is B: Endoplasmic reticulum. Prokaryotic cells lack membrane-bound organelles like the endoplasmic reticulum, which is present in eukaryotic cells. Prokaryotes do possess ribosomes for protein synthesis (A), a chromosome (C) for genetic material, and peptidoglycan (D) in their cell walls. The absence of endoplasmic reticulum is a key characteristic that distinguishes prokaryotic cells from eukaryotic cells.

Correct Answer: B

Rationale: B cells develop in the bone marrow, not the thymus. Firstly, hematopoietic stem cells in the bone marrow give rise to B cells. They undergo maturation and selection processes in the bone marrow, not in the thymus. Therefore, choice B is false. On the other hand, choices A, C, and D are correct. A is true because B cells with high affinity to self-antigens undergo apoptosis to prevent autoimmunity. C is true since B cells synthesize antibodies which can be displayed on their surface as B cell receptors. D is true because B cells can undergo class switching to produce different types of antibodies based on the immune response requirements.

Correct Answer: D

Rationale: The correct answer is D because Streptococci are Gram-positive bacteria, typically spherical in shape, and range from 0.5-1 µm in size. A is incorrect as streptococci are not rod-shaped and are usually smaller in size. B is incorrect as they are not Gram-negative and are not typically of such small size. C is incorrect as streptococci are not Gram-negative and are not usually rod-shaped. Thus, based on their characteristics, the correct answer is D.

Correct Answer: C

Rationale: The correct answer is C: Disk-diffusion test. In the disk-diffusion test, the zone of inhibition refers to the area around an antimicrobial disk where bacterial growth is inhibited. This test is used to determine the susceptibility of bacteria to specific antibiotics. The other choices, such as A: Use-dilution test, B: Growth inhibition test, and D: Multiple inhibition test, do not specifically involve measuring the zone of inhibition and are not commonly used methods for testing antibiotic susceptibility.

Correct Answer: D

Rationale: The correct answer is D. Isoniazid inhibits pyridoxal phosphate synthesis, which is the active form of vitamin B6. Pyridoxal phosphate is essential for various enzymatic reactions, including neurotransmitter synthesis and myelin formation. Therefore, isoniazid-induced pyridoxal phosphate deficiency can lead to neurological symptoms like polyneuritis, paresthesia, memory disorders, and convulsions. A: Disruption of cell membrane synthesis - This is not the mechanism of isoniazid side-effects. B: Inhibition of protein synthesis - Isoniazid does not directly inhibit protein synthesis. C: Inhibition of RNA-synthesis - Isoniazid does not inhibit RNA synthesis; it affects vitamin B6 metabolism.

Correct Answer: B

Rationale: The correct answer is B because enriched growth media provide essential nutrients that support the growth of target bacteria groups without inhibiting the growth of other microorganisms. This allows for the selective cultivation of specific microbes while still allowing for the growth of other organisms present in the sample. Choice A is incorrect because enriched media do not belong to minimal media and do not inhibit the development of gram+ cocci. Choice C is incorrect because enriched media can support the growth of multiple microbial species. Choice D is incorrect because enriched media do not suppress the development of other microorganisms but rather provide nutrients to support their growth alongside the target bacteria groups.

Correct Answer: C

Rationale: Rationale for choice C (Strep. pneumoniae): 1. Strep. pneumoniae is a common cause of bacterial meningitis. 2. It is a leading pathogen responsible for meningitis in adults and children. 3. It can invade the bloodstream and reach the meninges, causing inflammation. 4. Treatment guidelines often include antibiotics effective against Strep. pneumoniae. Summary of why other choices are incorrect: A. Staph. aureus is not a common cause of meningitis. B. Strep. pyogenes typically causes streptococcal infections but not meningitis. D. "None of the above" is incorrect as Strep. pneumoniae can cause meningitis.

Correct Answer: C

Rationale: The correct answer is C: Thermophiles. Thermophiles are bacteria that thrive in high temperatures, typically between 45-80 degrees Celsius. They have adapted to extreme heat environments and have enzymes that function optimally at high temperatures. Mesophiles (A) grow best at moderate temperatures, Psychrophiles (B) thrive in cold temperatures, and Halophiles (D) thrive in high salt concentrations. Therefore, only Thermophiles are specifically adapted to high temperatures, making it the correct choice.