The innate immune system is always working to protect the body and does not require any special preparation to stop infection:

Correct Answer: A

Rationale: The correct answer is A: TRUE. The innate immune system is the body's first line of defense against infections and is always active, providing immediate protection without prior exposure to a specific pathogen. It includes physical barriers, such as skin and mucous membranes, and cellular components like phagocytes and natural killer cells. The innate immune response is nonspecific and rapid, providing a crucial initial defense against pathogens. Choice B is incorrect because the innate immune system is always active, even without any prior exposure to pathogens. Choice C is incorrect because the innate immune system is consistently functioning to protect the body, regardless of the situation. Choice D is incorrect as the correct answer is A.

Correct Answer: D

Rationale: The correct answer is D because Streptococci are Gram-positive bacteria, typically spherical in shape, and range from 0.5-1 µm in size. A is incorrect as streptococci are not rod-shaped and are usually smaller in size. B is incorrect as they are not Gram-negative and are not typically of such small size. C is incorrect as streptococci are not Gram-negative and are not usually rod-shaped. Thus, based on their characteristics, the correct answer is D.

Correct Answer: A

Rationale: The correct answer is A: Syphilis. Hutchinson's triad is a classic presentation of congenital syphilis in children. Barrel-shaped incisors, parenchymatous keratitis, and deafness are key manifestations. Barrel-shaped incisors result from mulberry molars, a type of abnormal tooth. Parenchymatous keratitis is an inflammation of the cornea, a common ocular sign in congenital syphilis. Deafness can occur due to damage to the auditory nerve caused by the infection. Choices B, C, and D are incorrect as they do not typically present with the specific triad of symptoms seen in congenital syphilis.

Correct Answer: B

Rationale: B cells develop in the bone marrow, not the thymus. Firstly, hematopoietic stem cells in the bone marrow give rise to B cells. They undergo maturation and selection processes in the bone marrow, not in the thymus. Therefore, choice B is false. On the other hand, choices A, C, and D are correct. A is true because B cells with high affinity to self-antigens undergo apoptosis to prevent autoimmunity. C is true since B cells synthesize antibodies which can be displayed on their surface as B cell receptors. D is true because B cells can undergo class switching to produce different types of antibodies based on the immune response requirements.

Correct Answer: A

Rationale: The correct answer is A: Enteropathogenic E. Coli (EPEC). EPEC bacteria adhere to the intestine wall using a protein called intimin, leading to microvilli damage. This attachment disrupts the normal absorption function of the intestine. Summary of why other choices are incorrect: B: Enterohemorrhagic E. Coli (EHEC) primarily causes bloody diarrhea and does not specifically target microvilli. C: Enterotoxigenic E. Coli (ETEC) produces toxins that lead to watery diarrhea but does not directly target microvilli. D: Enteroinvasive E. Coli (EIEC) invades and replicates within intestinal cells, causing inflammatory diarrhea, but does not specifically damage microvilli.

Correct Answer: A

Rationale: The correct answer is A: Metronidazole. Metronidazole is a synthetic antiprotozoan drug with high activity against Helicobacter pylori, a bacterium that can cause wound infections. Metronidazole specifically targets anaerobic bacteria like H. pylori, making it effective in preventing wound infections. Incorrect choices: B: Doxycycline hydrochloride - Doxycycline is primarily used for bacterial infections, not protozoan infections like H. pylori. C: Chingamin - Chingamin is not a commonly used drug for treating H. pylori infections or preventing wound infections. D: Acyclovir - Acyclovir is an antiviral drug used to treat herpes infections, not bacterial or protozoan infections like H. pylori.

Correct Answer: C

Rationale: Rationale: 1. Presence of gram-negative bacilli suggests Enterobacteriaceae family, which includes E. coli. 2. Green soluble pigment indicates pyocyanin production, characteristic of E. coli. 3. E. coli is the most common cause of acute cystitis due to its ability to colonize the urinary tract. Summary: A: Pseudomonas aeruginosa is not typically associated with acute cystitis and does not produce mucous colonies. B: Klebsiella pneumoniae may cause UTIs, but does not produce green pigment and is less common than E. coli. D: Salmonella enteritidis is associated with gastrointestinal infections, not cystitis.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. 1. Gram-positive cocci in chains suggest streptococci. 2. Catalase-negative indicates it's not staphylococci. 3. Beta-hemolytic points towards Group A Streptococcus (S. pyogenes). Summary: B. Streptococcus pneumoniae is not beta-hemolytic. C. Enterococcus faecalis is not typically chains. D. Staphylococcus aureus is catalase-positive.

Correct Answer: D

Rationale: The correct answer is D. Isoniazid inhibits pyridoxal phosphate synthesis, which is the active form of vitamin B6. Pyridoxal phosphate is essential for various enzymatic reactions, including neurotransmitter synthesis and myelin formation. Therefore, isoniazid-induced pyridoxal phosphate deficiency can lead to neurological symptoms like polyneuritis, paresthesia, memory disorders, and convulsions. A: Disruption of cell membrane synthesis - This is not the mechanism of isoniazid side-effects. B: Inhibition of protein synthesis - Isoniazid does not directly inhibit protein synthesis. C: Inhibition of RNA-synthesis - Isoniazid does not inhibit RNA synthesis; it affects vitamin B6 metabolism.