ATI RN
Immune System ATI Quizlet Questions
Question 1 of 5
The immunoglobulin Joining chain (J-chain) is
Correct Answer: C
Rationale: Step-by-step rationale: 1. The J-chain is a polypeptide involved in the formation of polymeric IgM and IgA. 2. Polymeric forms of IgM and IgA contain the J-chain, aiding in their multimeric structure. 3. The J-chain is not exclusive to T-cells or neutrophils, making choices A and B incorrect. 4. IgE is associated with FcεRI receptors for histamine release, so choice D is incorrect. Summary: The correct answer is C because the J-chain is specifically associated with the multimeric forms of IgM and IgA, helping to form their structure. Choices A, B, and D are incorrect as the J-chain is not solely produced by T-cells, neutrophils, or associated with IgE for histamine release.
Question 2 of 5
The patient in a long arm cast (from below the shoulder to the wrist, with a 90-degree elbow flexion) complains of a burning sensation over the elbow. The nurse's initial intervention should be:
Correct Answer: B
Rationale: The correct answer is B: Check to see if the cast is properly supported. The burning sensation over the elbow could indicate nerve compression due to improper cast positioning. By checking if the cast is properly supported, the nurse can ensure that there is no pressure on the nerves causing the burning sensation. Elevating the casted arm (choice A) may not address the root cause of the burning sensation. Notifying the charge nurse of developing pressure ulcer (choice C) is premature without confirming the cause of the burning sensation. Cutting a "window" in the cast (choice D) should be a last resort after ruling out other issues.
Question 3 of 5
Which of the following statements is NOT true
Correct Answer: D
Rationale: The correct answer is D because CD3 is indeed necessary for TCR signaling in cytotoxic T cells. CD3 is a crucial component of the T cell receptor (TCR) complex, which is responsible for initiating intracellular signaling upon recognition of antigen-MHC complexes. Without CD3, TCR signaling cannot occur, leading to impaired T cell activation and cytotoxic function. Choices A, B, and C are incorrect because they accurately describe the functions and interactions of T cells expressing CD4 and CD8 with antigen presenting cells, as well as the role of CD4 T cells in helping B cells through antigen presentation.
Question 4 of 5
Which of the following concerned with Leishmania is NOT true
Correct Answer: a
Rationale: The correct answer is A: Mediated by IgE. Leishmania infection is not primarily mediated by IgE antibodies. The immune response against Leishmania involves T cells, macrophages, and cytokines. IgE is not a major player in the defense against Leishmania. Choices B, C, and D are incorrect because Leishmania is indeed a unicellular parasite, activation of macrophages is essential for killing the parasite, and Leishmania can hide inside neutrophils to escape the host immune attack.
Question 5 of 5
Which of the following statements is true about T regulatory cells
Correct Answer: A
Rationale: Rationale: A. T regulatory cells can produce TGF-β, which is a key immunosuppressive cytokine regulating immune responses. B. T regulatory cells do not express AIRE, a transcription factor mainly involved in central tolerance. C. T regulatory cells can control both TH1 and TH2 responses, maintaining immune homeostasis. D. T regulatory cells do not act by killing other T cell subsets, but rather through suppressive cytokines and cell-cell interactions.