The group of nicotinic receptor-blocking drugs consists of:

Correct Answer: D

Rationale: The correct answer is D because ganglion-blockers (A) and neuromuscular junction blockers (C) both belong to the group of nicotinic receptor-blocking drugs. Ganglion-blockers act on nicotinic receptors in autonomic ganglia, while neuromuscular junction blockers act on nicotinic receptors at the neuromuscular junction. Atropine-similar drugs (B) do not directly block nicotinic receptors, so they are not part of this particular group of drugs. Therefore, choices A and C cover all the drugs that block nicotinic receptors, making D the correct answer.

Correct Answer: C

Rationale: Rationale: Isoproterenol is a non-selective beta-adrenergic agonist that primarily acts on beta-1 and beta-2 receptors. It increases heart rate and contractility, leading to an increase in cardiac output (A) and tachycardia (D). Isoproterenol causes vasodilation, resulting in a fall in diastolic and mean arterial pressure (B). However, it does not cause bronchoconstriction (C) as it stimulates beta-2 receptors leading to bronchodilation. Therefore, the correct answer is C.

Correct Answer: C

Rationale: Rationale: Propranolol is a non-selective beta-blocker that can block beta-2 receptors leading to bronchoconstriction (A). Rapid withdrawal can cause beta-adrenergic receptor supersensitivity (B). Propranolol can cause sedation, sleep disturbances, depression, and sexual dysfunction (D). However, propranolol is associated with hypoglycemia, not hyperglycemia. Therefore, the correct answer is C.

Correct Answer: D

Rationale: The correct answer is D because benzodiazepines, while effective for insomnia, have the potential for psychological and physiological dependence (A), can cause synergistic depression of the central nervous system when combined with other drugs like alcohol (B), and may result in residual drowsiness and daytime sedation (C). Each of these factors poses risks and side effects associated with the use of benzodiazepines for treating insomnia. Therefore, the answer choice D, which includes all of the above factors, is the correct choice.

Correct Answer: A

Rationale: The correct answer is A: Respiratory depression. After large overdoses of antiseizure drugs, the most dangerous effect is respiratory depression due to the suppression of the central nervous system. This can lead to decreased breathing rate and potentially fatal consequences. Gastrointestinal irritation (B) and alopecia (C) are not typically associated with antiseizure drug overdoses. Sedation (D) may occur but is not as immediately life-threatening as respiratory depression in this context.