The goal of androgen therapy in men is to

Correct Answer: D

Rationale: Androgen therapy, typically testosterone, aims to increase libido and treat erectile dysfunction in men with hypogonadism, restoring sexual drive. Decreasing libido opposes its intent. It doesn't release FSH or increase LH-exogenous testosterone suppresses these via feedback. Boosting libido corrects deficiency symptoms, improving quality of life, a primary clinical goal.

Correct Answer: C

Rationale: Seizure drugs (e.g., benzodiazepines like clonazepam) treat anxiety via GABA enhancement, calming overactivity, per pharmacology. Antitussives suppress cough, anticoagulants thin blood, and antibiotics fight infection-none target anxiety. Seizure drugs' anxiolytic use is established, fitting the need.

Correct Answer: A

Rationale: Post-kidney transplant, immunosuppression prevents rejection by targeting T-cell activation. Cyclosporine binds calcineurin, inhibiting its phosphatase activity, which blocks IL-2 transcription, crucial for T-cell proliferation-making it the correct answer. Methotrexate inhibits purine synthesis, affecting rapidly dividing cells, not calcineurin. Prednisolone , a corticosteroid, suppresses inflammation broadly but doesn't target calcineurin. Sirolimus inhibits mTOR, a different pathway, affecting T-cell proliferation downstream, not calcineurin. Temsirolimus (E) is similar to sirolimus. Cyclosporine's specificity to calcineurin aligns with the question's focus, a cornerstone in transplant regimens. Its mechanism disrupts early T-cell signaling, critical for alloimmune responses, unlike the broader or alternative actions of other options. This precision ensures effective prophylaxis while distinguishing it from other immunosuppressants in the list.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.