ATI RN
NCLEX Pediatric Immunization Questions Questions
Question 1 of 5
The genes encoding which of the following are extensively polymorphic (have multiple alleles or forms of the same gene)?
Correct Answer: C
Rationale: MHC genes are highly polymorphic, providing diverse antigen presentation across populations, unlike BCR or TCR genes.
Question 2 of 5
Binds to various cellular receptors and to complement
Correct Answer: D
Rationale: The Fc region interacts with receptors on immune cells and complement proteins.
Question 3 of 5
Papain cleaves what region of immunoglobulin?
Correct Answer: C
Rationale: Papain cleaves above the hinge region, yielding two Fab fragments and one Fc.
Question 4 of 5
Which of the following is used to characterize antigens in complex mixtures biochemically?
Correct Answer: D
Rationale: Western blotting separates proteins by size and uses antibodies to characterize antigens biochemically in complex mixtures.
Question 5 of 5
In somatic recombination, the rearranges first. The region of the antibody molecule is generated via somatic recombination as it binds to the antigen and contains both a constant region and a variable region.
Correct Answer: A
Rationale: The heavy chain rearranges first, and the Fab region, which binds antigen, is generated via somatic recombination.