ATI RN
Chapter 2 pharmacologic principles Questions
Question 1 of 5
The following statements concerning renal drug handling are correct:
Correct Answer: A
Rationale: Kidneys receive ~20\% of cardiac output (A), ~1 L/min, driving filtration. Option B is true (GFR ~120-130 mL/min). Option C is correct (free drug filters). Option D is valid (active secretion). Option E (original) is false (low lipid solubility reduces reabsorption). High renal blood flow, critical in pharmacokinetics, ensures drug delivery for excretion, a foundational renal handling principle.
Question 2 of 5
Drugs with small volume of distribution (Vd) are characterized by
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
When drug/drug interactions involve inhibition of metabolism, which of the following types of drugs are of the most concern?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
The following is not true concerning factors affecting drug clearance
Correct Answer: E
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Represents rate & extent of drug absorption as measured by area under curve
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.