ATI RN
Pharmacology CNS Drugs Quiz Questions
Question 1 of 5
The following statements about carbidopa is CORRECT:
Correct Answer: A
Rationale: Carbidopa (choice A) inhibits dopa decarboxylase peripherally, preventing L-DOPA breakdown, enhancing CNS delivery in Parkinson's. It doesn't cross the BBB (choice B), reduces L-DOPA dose needs (choice C incorrect), and decreases peripheral metabolism (choice D incorrect). This correct statement underscores its adjunctive role.
Question 2 of 5
L-Dopa can be used to treat which of the following:
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Which of the following narcotics has the longest duration of effect?
Correct Answer: A
Rationale: Methadone (choice A), with a half-life of 24-36 hours, has the longest duration among these narcotics, ideal for addiction maintenance. Controlled-release morphine (choice B) lasts 12-24 hours, Levorphanol (choice C) 6-8 hours, and Fentanyl (choice D) 1-2 hours IV. Methadone's pharmacokinetics stand out.
Question 4 of 5
Which one of the following drugs can cause hypotension because it can block alpha-adrenergic receptors on vascular smooth muscle cells?
Correct Answer: D
Rationale: Phenothiazines (choice D), like chlorpromazine, block alpha-adrenergic receptors, causing vasodilation and hypotension. Clozapine (choice A) causes less alpha blockade, Diazepam (choice B) doesn't, and H1 blockers (choice C) cause sedation, not hypotension. This side effect is notable in phenothiazines.
Question 5 of 5
Which of the following antipsychotic medications has the greatest potential for extrapyramidal side effects?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.