ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
The following receptors are affected by antipsychotic drugs EXCEPT:
Correct Answer: C
Rationale: Antipsychotics (e.g., haloperidol) block central D2 (choice A) and 5-HT2 receptors (choice B) for efficacy, and muscarinic receptors (choice D) peripherally, causing side effects. Peripheral H2 receptors (choice C), involved in gastric acid secretion, aren't significantly affected; H1 antagonism occurs instead. This exception clarifies antipsychotic receptor profiles.
Question 2 of 5
Which of the following is a GABA transaminase inhibitor?
Correct Answer: B
Rationale: Vigabatrin inhibits GABA transaminase
Question 3 of 5
A 73-year-old man presents to his primary care physician complaining of a weak stream and nocturia four times at night. He is very sensitive to the medication side effects and is reluctant to take medications for this reason. Physical examination reveals a mildly enlarged prostate. Treatment of this condition may involve the use of which of the following agents to minimize side effects?
Correct Answer: D
Rationale: Tamsulosin is an α1-adrenergic receptor antagonist that is selective for the prostate and bladder neck, minimizing systemic side effects like hypotension.
Question 4 of 5
Which of the following antipsychotics (in excess dose) is responsible for cardiac arrhythmias?
Correct Answer: C
Rationale: Thioridazine has been associated with QT prolongation and a higher risk of cardiac arrhythmias.
Question 5 of 5
Which of the following antipsychotics (in excess dose) is responsible for cardiac arrhythmias?
Correct Answer: C
Rationale: Thioridazine has been associated with QT prolongation and a higher risk of cardiac arrhythmias.