The following NSAID is concentrated in synovial fluid 4 times more than plasma:

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Central Nervous System Stimulants and Related Drugs NCLEX Questions Quizlet Questions

Question 1 of 5

The following NSAID is concentrated in synovial fluid 4 times more than plasma:

Correct Answer: A

Rationale: Diclofenac (choice A) concentrates in synovial fluid, enhancing its efficacy in joint inflammation (e.g., arthritis). Aspirin (choice B) and Acetaminophen (choice D) don't target synovial fluid significantly. Codeine (choice C), an opioid, lacks anti-inflammatory action. Diclofenac's pharmacokinetics suit musculoskeletal conditions.

Question 2 of 5

Gold compounds have been used to treat:

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Which of the following action(s) is produced by lorazepam:

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

All of the following are side effects associated with the use of lithium EXCEPT:

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

A patient was treated with a drug and after the addition of another drug by his physician, the patient developed 'hyperthermia, muscle rigidity and rapid changes in mental conditions' and the case was diagnosed as serotonin syndrome. Which of the following combination of drugs was the most likely cause of these adverse effects?

Correct Answer: D

Rationale: MAOI + Fluoxetine (choice D) causes serotonin syndrome (hyperthermia, rigidity, mental changes) by excessive serotonin from MAOI preventing breakdown and SSRI blocking reuptake. Diazepam + Flumazenil (choice A), Morphine + Methadone (choice B), and L-DOPA + Carbidopa (choice C) don't target serotonin. This interaction is severe.

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