ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
The following is NOT an advantage of rivaroxiban and dabigatran over warfarin:
Correct Answer: C
Rationale: Rivaroxaban and dabigatran have rapid onset/offset, no INR monitoring, and fewer CYP450 interactions, but both require dose adjustments in renal failure due to renal clearance, unlike warfarin.
Question 2 of 5
Reduction in calcium absorption from GIT is associated with the use of:
Correct Answer: D
Rationale: Alendronate (bisphosphonate) and prednisone (glucocorticoid) reduce GI calcium absorption; raloxifene doesn’t, and alfacalcidiol (vitamin D) enhances it.
Question 3 of 5
The following is (are) used in acromegaly and in Parkinsonism:
Correct Answer: D
Rationale: Bromocriptine (D2 agonist) treats acromegaly (reduces GH) and Parkinsonism (mimics dopamine). L-dopa also treats Parkinsonism. Octreotide is for acromegaly only.
Question 4 of 5
The following is WRONG concerning leuprolide & nafarelin:
Correct Answer: D
Rationale: Leuprolide and nafarelin (GnRH analogs) stimulate ovulation in pulses for infertility and inhibit gonadotropins continuously for prostate cancer. Continuous use, not pulses, treats endometriosis by suppressing estrogen.
Question 5 of 5
The following is Wrong concerning selective estrogen receptor modulators:
Correct Answer: B
Rationale: Tamoxifen treats breast cancer, not uterine cancer (it increases endometrial cancer risk). Clomiphene induces ovulation, raloxifene treats osteoporosis with thromboembolism risk, and clomiphene causes multiple pregnancies.