ATI RN
ABVD chemotherapy drugs Questions
Question 1 of 5
The following is INCORRECT about dabigatran:
Correct Answer: A
Rationale: Dabigatran has a rapid onset (~1-2 hours) but its half-life is 12-17 hours, not up to 6 days. PPIs reduce absorption, it’s safer in liver failure than warfarin, it’s dialyzable, and idarucizumab is its antidote.
Question 2 of 5
The following concerning drugs used in osteoporosis is wrong:
Correct Answer: B
Rationale: Calcitonin, raloxifene, and alendronate reduce resorption; teriparatide and steroids increase formation; strontium is for severe cases; denosumab reduces resorption. Fluorides increase bone density but don’t substitute for calcium.
Question 3 of 5
The following is/are used in acromegaly & bleeding esophageal varices:
Correct Answer: D
Rationale: Octreotide (somatostatin analog) and terlipressin (vasopressin analog) reduce GH in acromegaly and portal pressure in varices. Bromocriptine and L-dopa don’t treat varices.
Question 4 of 5
True statement (s) concerning octreotide:
Correct Answer: D
Rationale: Octreotide, a long-acting somatostatin analog, inhibits GH, GIT hormones, and glucagon, making it effective against VIPomas, gastrinomas, and glucagonomas.
Question 5 of 5
An agent used in treatment of infertility that blocks hypothalamic estrogen receptors preventing normal feedback inhibition of FSHRH & LHRH:
Correct Answer: A
Rationale: Clomiphene blocks hypothalamic estrogen receptors, increasing GnRH, FSH, and LH to stimulate ovulation in infertility.