The following is/are true about Cervarix:

Correct Answer: B

Rationale: In this question about Cervarix, the correct answer is B) If the 2-dose course is interrupted, it should be resumed but not repeated. This answer is correct because Cervarix is a vaccine used to protect against certain strains of human papillomavirus (HPV), not genital warts. Option A is incorrect because Cervarix does not provide protection against genital warts; it specifically targets HPV. Option C is incorrect because Cervarix is supplied as a suspension of virus-like particles (VLPs), but not in a pre-filled syringe. Option D is incorrect because Cervarix contains HPV types 16 and 18, not 11 and 16. Educationally, understanding the specifics of vaccines like Cervarix is crucial in infection prevention and control. Nurses and healthcare providers must be knowledgeable about vaccine indications, administration, and characteristics to ensure proper immunization practices and patient education. This question reinforces the importance of accuracy in vaccine information to maintain patient safety and prevent the spread of infectious diseases.

Correct Answer: A

Rationale: The correct answer is A) IXIARO is licensed for individuals aged 2 months and older. This statement is true because IXIARO is indeed approved for use in individuals starting from 2 months of age according to the CDC guidelines for Japanese Encephalitis (JE) vaccination. Option B is incorrect because the recommended schedule for children aged 24 months is actually a single 0.5 ml dose of IXIARO on days 0 and 28. Option C is also incorrect as the primary schedule for IXIARO consists of 2 doses, not 3. Option D is incorrect because primary vaccination should ideally be completed at least 10 days before potential exposure to JE virus, not just one week. In an educational context, understanding the correct dosing schedule for vaccines like IXIARO is crucial for healthcare professionals to ensure proper administration and protection against infectious diseases like Japanese Encephalitis. This knowledge is vital for nurses, doctors, and other healthcare providers to accurately advise and vaccinate patients, ultimately contributing to effective infection prevention and control practices.

Correct Answer: C

Rationale: The correct answer is C) Other people with severe immuno-compromising conditions. Meningococcal vaccines are contraindicated in individuals with severe immunocompromising conditions because they may not have an adequate immune response to the vaccine, rendering it ineffective. These individuals may not be able to mount a strong enough immune response to develop immunity against the disease. Option A) Pregnant women: Meningococcal vaccines are generally safe for pregnant women, especially if they are at increased risk of exposure to the bacteria. Option B) HIV positive people: HIV positive individuals are at higher risk of contracting meningococcal disease, so they are actually recommended to receive the vaccine to protect themselves. Option D) Premature infants: Premature infants are not contraindicated to receive the meningococcal vaccine. In fact, they may be at higher risk of severe complications from meningococcal disease, so vaccination is important for their protection. Educational Context: Understanding contraindications for vaccines is crucial in clinical practice to ensure the safety and efficacy of vaccination. Healthcare providers need to be aware of who should not receive certain vaccines based on their medical conditions to prevent adverse reactions and ensure optimal protection against vaccine-preventable diseases. This knowledge is also important for passing exams like the NCLEX, where questions regarding contraindications for vaccines may be asked.

Correct Answer: B

Rationale: The correct answer is B) In the routine immunization schedule, the 4C Men B protein vaccine (Bexsero®) is given at 2 and 4 months with a booster at 12-13 months. This is the correct option because the vaccine schedule for Bexsero® follows this specific timing for optimal protection against meningococcal disease caused by serogroup B. By administering the vaccine at these intervals, the individual receives the necessary doses to develop a robust immune response. Option A is incorrect because the 4C Men B protein vaccine is not supplied as a vial of white powder with a separate diluent. It is usually a pre-filled syringe that does not require reconstitution. Option C is incorrect as the vaccine schedule does not include doses at 2, 3, and 4 months but rather at 2 and 4 months with a booster later. Option D is also incorrect because the vaccine is not recommended as a single dose for students attending university for the first time; instead, it follows the recommended schedule for infants and young children. In an educational context, understanding the correct vaccine schedule is crucial for healthcare professionals, especially nurses and doctors involved in administering vaccines. Knowledge of the specific dosing intervals and schedules ensures that individuals receive the full benefit of the vaccine and are adequately protected against meningococcal disease. Educating healthcare providers on vaccine schedules helps in effective immunization practices and ultimately in preventing the spread of infectious diseases.

Correct Answer: B

Rationale: The correct answer is B) Appears to produce 'herd immunity'. Explanation: Pneumococcal conjugate vaccine (PCV) is known to contribute to herd immunity by reducing the overall prevalence of the disease within a community. This phenomenon occurs when a significant portion of the population becomes immune to a specific infectious agent, thereby protecting those who are not immune, such as individuals who cannot be vaccinated due to medical reasons or have not yet received the vaccine. Why the other options are incorrect: A) Children require more than one dose to produce effective protection: While multiple doses of the vaccine may be necessary to provide optimal protection, this statement does not specifically address the concept of herd immunity associated with PCV. C) Contains thiomersal: This option is incorrect as PCV vaccines in the United States do not contain thiomersal, which is a preservative that has been removed from most vaccines due to safety concerns. D) Is available which covers 13 serotypes: While this statement is factual about the composition of some PCV vaccines, it does not address the concept of herd immunity, which was the focus of the question. Educational context: Understanding the impact of vaccines on population health is crucial for healthcare professionals, especially in the context of infection prevention and control. By recognizing how vaccines like PCV can contribute to herd immunity, nurses and other healthcare providers can better advocate for vaccination programs and educate patients and families about the importance of immunization in protecting both individuals and communities from infectious diseases.