ATI RN
Chemotherapy drugs Questions
Question 1 of 5
The following helminthic disease can be treated by albendazole but not by mebendazole
Correct Answer: D
Rationale: Albendazole treats neurocysticercosis (unlike mebendazole) due to better CNS penetration.
Question 2 of 5
The following are 1st line anti-tuberculous drugs except:
Correct Answer: B
Rationale: First-line anti-TB drugs include isoniazid, rifampicin, ethambutol, and pyrazinamide. Cycloserine is a second-line drug used for resistant TB, not a first-line treatment.
Question 3 of 5
All the following antifungal drugs are antibiotics, EXCEPT:
Correct Answer: C
Rationale: Amphotericin B, nystatin, and griseofulvin are antibiotics derived from fungi, whereas miconazole is a synthetic azole antifungal, not an antibiotic.
Question 4 of 5
Which of the following drugs alters permeability of Candida cell membranes:
Correct Answer: C
Rationale: Nystatin, like amphotericin B, binds ergosterol in Candida cell membranes, altering permeability and causing cell death, while ketoconazole inhibits ergosterol synthesis.
Question 5 of 5
Mechanism of Isoniazid action is:
Correct Answer: B
Rationale: Isoniazid inhibits mycolic acid synthesis in Mycobacterium tuberculosis by targeting InhA and KatG, disrupting cell wall formation, a key mechanism in TB treatment.